Results 171 to 180 of about 991,414 (299)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Interpreting Performance of Deep Neural Networks with Partial Information Decomposition. [PDF]

Entropy (Basel)
Liu T, Guo B, Yin Z, Mi Z, Jin D.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Inter-fraction dose and LET robustness in LET-optimized proton therapy for pediatric, adolescent and young adult intracranial tumors. [PDF]

Med Phys
Mirandola A, Bagnalasta M, Magro G, Bazani A, Molinelli S, Pavanello V, Rossi E, Russo S, Trombetta L, Vai A, Colombo F, Orlandi E, Ciocca M, Vennarini S.   +13 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

An ESTRO-EPTN Delphi consensus on robustness evaluation in proton therapy. [PDF]

Phys Imaging Radiat Oncol
Fracchiolla F, Meijers A, Orlandi E, Korevaar E, Whitfield G, Jensen K, Hoogeman M, Wijsman R, Jouglar E, Weerd EV, Pérez JM, Rinaldi I, Garbacz-Stryszewska M, Cianchetti M, Feijoo MM, Molinelli S, Elstrøm UV, Pica A, Gosling A, Koczur B, Dahlgren CV, Alterio D, Dale E, Farid G, Compter I, Doyen J, Dale JE, Färlin J, Urbanek K, Fjæra LF, Lambrecht M, Ugland M, Tschiche M, Vidal M, Lowe M, Bütof R, Gulliford S, Comi S, Habraken S, Tessonnier T, Sterpin E, Widesott L.   +41 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

HiRo-SLAM: A High-Accuracy and Robust Visual-Inertial SLAM System with Precise Camera Projection Modeling and Adaptive Feature Selection. [PDF]

Sensors (Basel)
Deng Y, Tian L, Hou X, Liu X, Wang Y, Liu X, Liao C.   +6 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Minimal time robust control for two superconducting qubits. [PDF]

Sci Rep
George N, Allen JL, Kosut R, Ginossar E.
europepmc   +1 more source