Results 101 to 110 of about 569,766 (265)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Analog Sequential Hippocampal Memory Model for Trajectory Learning and Recalling: A Robustness Analysis Overview

open access: yesAdvanced Intelligent Systems
The rapid expansion of information systems in all areas of society demands more powerful, efficient, and low‐energy consumption computing systems. Neuromorphic engineering has emerged as a solution that attempts to mimic the brain to incorporate its ...
Daniel Casanueva‐Morato   +4 more
doaj   +1 more source

Multi-vendor robustness analysis of a commercial artificial intelligence system for breast cancer detection. [PDF]

open access: yesJ Med Imaging (Bellingham), 2023
Riveira-Martin M   +3 more
europepmc   +1 more source

Robust Compositional Data Analysis

open access: yes, 2011
Many practical data sets contain outliers or other forms of data inhomogeneities. Robust statistics offers concepts how to deal with these situations where the data do not follow strict model assumptions. These concepts are designed for the usual Euclidean space, and they can be easily applied to compositional data if they are ...
Filzmoser, Peter   +2 more
openaire   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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