Results 41 to 50 of about 569,766 (265)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Composite inverse model ILC for discrete time linear systems: zero error in finite steps and uncertain initial conditions

Systems Science & Control Engineering
This paper develops iterative learning control strategies for discrete-time linear systems. An explicit state-space formula for the inverse-model-based ILC algorithm is derived under general conditions, which simplifies further when matrices B and C are ...
Jian Tan, Senping Tian, Jiaqi Xin
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Robustness and Convergence of a Stochastic Deterioration Prediction Model for Tunnel Lighting Facilities: A Japanese Case Study Based on Systematized Expert Knowledge and Large-Scale Monte Carlo Simulation

Applied Sciences
Much of Japan’s social infrastructure was concentrated during the period of rapid economic growth around the 1970s and is now facing the serious problem of simultaneous aging.
Yasuko Kawahata, Noriaki Maeda, Shunsuke Hatadani   +2 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Time-Optimal Route Planning for Electric Ships in Stochastic Seas via PMP–HJB Equivalence

IEEE Access
We propose an integrated framework for minimum-time return-to-origin routing of electric-propelled ships operating under uncertain wind, waves, and currents, with a particular focus on partial-failure conditions.
Jeonghyun Kwon, Hwa-Sup Jang, Tae-Hyun Lee, Yong-Jin Kim, Kyung-Ha Ryu, Young-Ki Kim, Jihyuk Park   +6 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Artificial Neural Network-Based Gain-Scheduled State Feedback Speed Controller for Synchronous Reluctance Motor

Power Electronics and Drives, 2021
This paper focuses on designing a gain-scheduled (G-S) state feedback controller (SFC) for synchronous reluctance motor (SynRM) speed control with non-linear inductance characteristics.
Tarczewski Tomasz, Niewiara Łukasz J., Grzesiak Lech M.   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source