Results 61 to 70 of about 569,766 (265)
IEEE Access, 2019 In this paper, atom search optimization (ASO) algorithm and a novel chaotic version of it [chaotic ASO (ChASO)] are proposed to determine the optimal parameters of the fractional-order proportional+integral+derivative (FOPID) controller for dc motor ...
Baran Hekimoglu
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Statistical Science, 2016 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
IEEE AccessUnderstanding how written musical structures relate to expressive timing decisions is central to computational performance analysis; however, existing explanation methods often rely on predictive models, surrogate learning, or input perturbation.
Ayako Minematsu, Takafumi Nakanishi
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Measuring LLM Self-consistency: Unknown Unknowns in Knowing Machines
SociologicaThis essay critically examines some limitations and misconceptions of Large Language Models (LLMs) in relation to knowledge and self-knowledge, particularly in the context of social sciences and humanities (SSH) research.
Mathieu Jacomy, Erik Borra
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A scenario-based alternative to conventional tools for choosing the strategy in turbulent environments [PDF]
International Journal of Research in Industrial EngineeringStrategic decision-making is often complex and uncertain, especially in turbulent environments. A large number of frequently conflicting indicators, rapid and unpredictable environmental changes, and the long-term consequences of making a decision have ...
Ali Sorourkhah
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