Results 41 to 50 of about 562,683 (296)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Reliability-Based Robust Design Optimization for Maximizing the Output Torque of Brushless Direct Current (BLDC) Motors Considering Manufacturing Uncertainty

Machines, 2022
In recent years, the deterministic design optimization method has been widely used to improve the output performance of brushless direct current (BLDC) motors.
Kyunghun Jeon, Donghyeon Yoo, Jongjin Park, Ki-Deok Lee, Jeong-Jong Lee, Chang-Wan Kim   +5 more
doaj   +1 more source

Design and Development of Software Tools for Bio-PEPA [PDF]

, 2009
This paper surveys the design of software tools for the Bio-PEPA process algebra. Bio-PEPA is a high-level language for modelling biological systems such as metabolic pathways and other biochemical reaction networks.
Duguid, Adam, Gilmore, Stephen, Guerriero, Maria, Hillston, Jane, Loewe, Laurence   +4 more
core   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Robustness and Reliability of Federated Learning

, 2022
Federated Learning (FL) is a newly introduced distributed learning scheme, which is designed with users' privacy in mind, by never collecting clients' data during the training process. FL's process starts with the server sending a model to clients, then the clients train that model using their local data and send the updated model back to the server ...
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Reliability-based approach to the robustness of corroded reinforced concrete structures [PDF]

, 2017
Currently, decisions on the maintenance and repair of infrastructural assets, structures in particular, are mostly based on the results of inspections and the resulting condition index, neglecting system robustness and therefore not making optimal use of
Al-Hammoud, Almusallam, Almusallam, Baker, Bhargava, Biondini, Bucher, Cairns, Cavaco, Ditlevsen, Frangopol, Gomes, Lind, Mangat, Melchers, Melchers, Molina, Murakami, Oliver, Oliver, Oliver, Palsson, Schroeder, Starossek, Stewart, Stewart, Stewart, Strauss, Strauss, Sánchez, Val, Vu, Woodtli, Yalciner, Zimmermann   +34 more
core   +3 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Reliability analysis based on gradient and heuristic optimization techniques of composite laminates using element-free Galerkin method [PDF]

International Journal for Simulation and Multidisciplinary Design Optimization, 2008
This work presents a reliability methodology that couples gradient and heuristic based reliability methods with element-free Galerkin method applied in composite laminates structures.
Rojas J. E., El Hami A., Rade D. A.
doaj   +1 more source