Results 51 to 60 of about 562,683 (296)

Design of Automatically Adaptable Web Wrappers [PDF]

, 2011
Nowadays, the huge amount of information distributed through the Web motivates studying techniques to\ud be adopted in order to extract relevant data in an efficient and reliable way.
Baumgartner, Robert, Ferrara, Emilio
core   +1 more source

Exploring tradeoffs in pleiotropy and redundancy using evolutionary computing

, 2004
Evolutionary computation algorithms are increasingly being used to solve optimization problems as they have many advantages over traditional optimization algorithms.
Abbott, Derek, Allison, Andrew, Berryman, Matthew J., Khoo, Wei-Li, Nguyen, Hiep, O'Neill, Erin   +5 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Ultrathin bending sensor with ultrahigh robustness and reliability for robotic applications

npj Flexible Electronics
Soft bending sensors offer high sensitivity and a large deformation range, making them ideal for robotics and healthcare. However, existing sensors made from organic materials often fail under large tensile stresses and long-term bending, limiting their ...
Hao Liu, Masahito Takakuwa, Michitaka Yamamoto, Shinsuke Nakashima, Zhengyi Jiang, Tomoyuki Yokota, Takao Someya, Toshihiro Itoh, Seiichi Takamatsu   +8 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Robust control plane scheme in SDVN toward targeted attack

Dianzi Jishu Yingyong, 2022
Applying software-defined networking to the Internet of Vehicles can significantly improve its performance. However, this method also faces security issues that traditional SDN has to deal with.
Mao Ming, Yi Peng, Zhang Zhen, Ma Yun
doaj   +1 more source

An $hp$-Adaptive Newton-Galerkin Finite Element Procedure for Semilinear Boundary Value Problems

, 2016
In this paper we develop an $hp$-adaptive procedure for the numerical solution of general, semilinear elliptic boundary value problems in 1d, with possible singular perturbations. Our approach combines both a prediction-type adaptive Newton method and an
Amrein, Mario, Melenk, Jens M., Wihler, Thomas P.   +2 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Robustness and Efficiency Considerations When Testing Process Reliability with a Limit of Detection

Mathematics
Processes in biotechnology are considered reliable if they produce samples satisfying regulatory benchmarks. For example, laboratories may be required to show that levels of an undesirable analyte rarely (e.g., in less than 5% of samples) exceed a ...
Laura S. Bumbulis, Richard J. Cook
doaj   +1 more source

GPS baseline configuration design based on robustness analysis

Journal of Geodetic Science, 2012
The robustness analysis results obtained from a Global Positioning System (GPS) network are dramatically influenced by the configurationof the observed baselines. The selection of optimal GPS baselines may allow for a cost effective survey campaign and a
Yetkin M., Berber M.
doaj   +1 more source