Results 281 to 290 of about 578,574 (323)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Evolutionary Rate Incongruences in Squamates Reveal Contrasting Patterns of Evolutionary Novelties and Innovation. [PDF]

Syst Biol
Simões TR, Brum AS, Pierce SE.
europepmc   +1 more source

A novel hybridization of birds of prey-based optimization with differential evolution mutation and crossover for chaotic dynamics identification. [PDF]

Sci Rep
Ekinci S, Izci D, Kayri M, Elsayed F, Salman M.   +4 more
europepmc   +1 more source

A spatio-temporal self-supervised meta-learning network with dynamic graph learning for traffic flow forecasting. [PDF]

PLoS One
Qiu Q, Huang Y, Huang X, Zhou W.
europepmc   +1 more source

Macroscopic relationship among robustness, evolvablity, and phenotypic fluctuations(International & Interdisciplinary Symposium on What is Evolution? Bicentennial of Charles Darwin's Birth)

, 2010
Kunihiko Kaneko
openalex   +1 more source

Optimal capacity configuration of wind-photovoltaic-storage hybrid systems based on improved chaotic evolution optimization algorithm. [PDF]

Sci Rep
Dong Y, Zhou X, Cao X, Jiang J, He Y, Yin C.   +5 more
europepmc   +1 more source

Decoding the evolution of melodic and harmonic structure of Western music through the lens of network science. [PDF]

Sci Rep
Di Marco N, Loru E, Galeazzi A, Cinelli M, Quattrociocchi W.   +4 more
europepmc   +1 more source

Strategies for updating rules driven by reinforcement learning to solve social dilemmas. [PDF]

PLoS One
Wang Y, Yu X, Lu S.
europepmc   +1 more source

Punctuated evolution and robustness in morphogenesis [PDF]

BioSystems, 2014
This paper presents an analytic approach to the pattern stability and evolution problem in morphogenesis. The approach used here is based on the ideas from the gene and neural network theory. We assume that gene networks contain a number of small groups of genes (called hubs) controlling morphogenesis process.
D Grigoriev, J Reinitz, S Vakulenko
exaly   +4 more sources