Results 141 to 150 of about 862,452 (277)

Hierarchical Channeled Graphitized Nanoarchitecture as a Diagnostic Platform for Maternal Fever Warning

Advanced Science, EarlyView.
This study presents a hierarchically channeled graphitized nanoarchitecture (HPGC‐Z67) as a novel nano‐diagnostic platform. It enables sensitive and efficient N‐glycan extraction from plasma, significantly reducing processing time and cost. The platform identifies pivotal N‐glycans to accurately differentiate between infectious and non‐infectious ...
Yiwen Lin, Ning Li, Heyuhan Zhang, Xufang Hu, Zhiqiang Liu, Chunhui Deng   +5 more
wiley   +1 more source

ESM1 May Be Used as a New Indicator for the Diagnosis and Prognosis of Early and Advanced Stage Digestive Tract Cancers

International Journal of General Medicine
Kui Kang,1 Ying Wang,2 Bo Zhang,1 Zhengxing Xie,1 Sheng Qing,1 Yanan Di1 1Department of Gastroenterology, Beijing Aerospace General Hospital, Beijing, People’s Republic of China; 2Department of Endocrinology, Air Force Specialty Medical Center, Beijing ...
Kang K, Wang Y, Zhang B, Xie Z, Qing S, Di Y   +5 more
doaj  

Provider costs of Antiretroviral therapy (ART) in Zimbabwe: The value of using time-driven activity based costing methods in a low resource setting. [PDF]

PLoS One
Nyamasve JG, Pindiriri C, Mapako T, Ingwani A, Corbin S, Mugurungi O, Apollo T, Chikomo S, Chikambure K, Shamu S, Morrison L, Mujuru N, Boadi E, Peterson T, Chirenda J.   +14 more
europepmc   +1 more source

BADA-ROC

Ante una experiencia de cooperación interciudadana como la que aquí se muestra, nos decidimos a elaborar estos apuntes etnográficos que reflejan la forma en que se asienta una comunidad en torno a un fin común que no busca ningún beneficio material. Los resultados que se incluyen, forman parte de un material obtenido como producto de las labores de ...
Vázquez Atochero, Alfonso||, Rabazo Ortega, Rosa||   +1 more
openaire   +1 more source

Pancancer Fine‐Mapping of Mutational Intolerance Identifies CHEK1 as an Immunosuppressive Driver in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang, Hongyu Zhao, Xiaojie Sun, Yuqi Ding, Zhipeng Zhu, Xiaotong Yu, Rongyi Zhu, Dan Wang, Kailong Li, Yang Liu, Li‐Bin Wang, Xiaolu Zhao, Baojun Suo, Hongsen Bi, Peipei Zhang, Tong Liu, Fengbiao Mao   +16 more
wiley   +1 more source

An improved dataset for predicting mammal infecting viruses from genetic sequence information. [PDF]

PLoS Comput Biol
Reddy T, Schneider A, Hall AR, Witmer A, Hengartner N.   +4 more
europepmc   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Perceived Stress and Compassion Satisfaction Among Nurses: A Mediation Model of Perceived Disaster Preparedness. [PDF]

J Nurs Res
Chiang KJ, Chang LF, Chou LJ, Huang LC, Kao YL, Lin C, Chen YH, Hung AH, Pan HH.   +8 more
europepmc   +1 more source

Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS

Advanced Science, EarlyView.
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi, Di Tang, Johan Malmström, Yasaman Karami, Hamed Khakzad   +4 more
wiley   +1 more source

A pilot study of a novel portable mass spectrometer for rapid, simultaneous detection of multiple anesthetic drug concentrations. [PDF]

Front Vet Sci
Xie X, Li X, Zhang W.
europepmc   +1 more source