Results 141 to 150 of about 527,913 (313)
Beyond the ROC curve: application to a clinical study [PDF]
openIn questa tesi, si considera uno studio clinico su 619 pazienti affetti da asma con l’obiettivo di valutare la capacità di alcune variabili nella classificazione dei soggetti in tre gruppi: livello di asma ben controllato, livello parzialmente ...
MECENERO, LINDA
core
Advanced Science, EarlyView.Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang +11 more
wiley +1 more source
TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes
Advanced Science, EarlyView.In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang +11 more
wiley +1 more source
Advanced Science, EarlyView.In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li +10 more
wiley +1 more source
Accuracy of logistic models and receiver operating characteristic curves [PDF]
The accuracy of prediction is a commonly studied topic in modern statistics. The performance of a predictor is becoming increasingly more important as real-life decisions axe made on the basis of prediction.
Corbett, Philip
core
SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening
Advanced Science, EarlyView.Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen +20 more
wiley +1 more source
nonbinROC: Software for Evaluating Diagnostic Accuracies with Non-Binary Gold Standards [PDF]
ROC analysis is a standard method for estimating and comparing diagnostic tests' accuracies when the gold standard is binary. However, there are many situations when the gold standard is not binary.
Paul Nguyen
core +1 more source
Advanced Science, EarlyView.ABSTRACT Current prostate cancer detection methods remain limited in non‐invasiveness and specificity, prompting interest in urinary biomarkers such as sarcosine. Here, we report a urine‐powered wearable platform for non‐invasive sarcosine detection as a proof‐of‐concept for decentralized early warning.
Jing Xu +10 more
wiley +1 more source
Sustainable Materials Design With Multi‐Modal Artificial Intelligence
Advanced Science, EarlyView.Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu +8 more
wiley +1 more source
Regional Organizations Cooperation Mechanism for Trade Facilitation (ROC-TF) Newsletter. Issue IV, July 2013 [PDF]
, 2013 INSIDE THIS ISSUE : ROC-TF Updates 2 Project/Activity Update 3 Knowledge Products (Publications) 8 Upcoming Events 14 News ...
UN.ESCAP
core