Results 41 to 50 of about 862,452 (277)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Sistem Pendukung Keputusan Seleksi Penerima Program Keluarga Harapan dengan Implementasi Metode SAW dan Pembobotan ROC

open access: yesEmitor: Jurnal Teknik Elektro, 2022
Program Keluarga Harapan (PKH) sendiri merupakan salah satu upaya pemerintah untuk mempercepat pengentasan kemiskinan. Permasalahan yang ada saat ini proses penentuan penerima PKH yang dilakukan pengurus dan pendamping PKH di Desa Pucangan masih ...
Wulandari Ratna Kartika Jayawardani   +1 more
doaj   +1 more source

Designing a Comprehensive Model for Selecting the Best Fuel in Natural Gas Value Chain (A case study in Iran) [PDF]

open access: yesPizhūhishnāmah-i Iqtiṣād-i Inirzhī-i Īrān, 2020
The global interest in using natural gas has increased considerably, and some factors such as low cost, safety, availability, environmental advantages, technological development, and its applications especially for gas turbines, have caused petroleum ...
ahmad mosaee   +2 more
doaj   +1 more source

Automated Classification of Periodic Variable Stars detected by the Wide-field Infrared Survey Explorer [PDF]

open access: yes, 2014
We describe a methodology to classify periodic variable stars identified using photometric time-series measurements constructed from the Wide-field Infrared Survey Explorer (WISE) full-mission single-exposure Source Databases.
Cutri, Roc M.   +3 more
core   +3 more sources

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Long-lived quantum memory with nuclear atomic spins

open access: yes, 2005
We propose to store non-classical states of light into the macroscopic collective nuclear spin ($10^{18}$ atoms) of a $^3$He vapor, using metastability exchange collisions. These collisions, commonly used to transfer orientation from the metastable state
A. Dantan   +8 more
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Robust Orthogonal Complement Principal Component Analysis [PDF]

open access: yes, 2016
Recently, the robustification of principal component analysis has attracted lots of attention from statisticians, engineers and computer scientists. In this work we study the type of outliers that are not necessarily apparent in the original observation ...
Li, Shijie, She, Yiyuan, Wu, Dapeng
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

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