Results 121 to 130 of about 3,583,799 (330)

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

nonbinROC: Software for Evaluating Diagnostic Accuracies with Non-Binary Gold Standards [PDF]

ROC analysis is a standard method for estimating and comparing diagnostic tests' accuracies when the gold standard is binary. However, there are many situations when the gold standard is not binary.
Paul Nguyen
core  

ROC curve analysis.

, 2019
ROC curve analysis.
Jacob Hsiao Wen Yeo (6890246), Boon Leong Lan (169790)   +1 more
core   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

ROC curve for BW.

, 2019
ROC curve for BW.
Kurthan Mert (6817961), Canan Aygun (6817946), Tulin Gokmen (6817964), Sezin Unal (6817955), Ugur Kayacan (6817931), Barıs Akcan (6817967), Yalcın Celik (6817928), Umut Zubarioglu (6817952), Mehmet Satar (6817940), Servet Ozkiraz (6817949), Begum Atasay (4884871), Hatice Turgut (6817958), Hilal Ozkan (6817934), Gaffari Tunc (4884895), Emel Okulu (4884880), Saadet Arsan (4884892), Mustafa Akcali (6817943), Omer Erdeve (4884868), Merih Cetinkaya (734526), Gokhan Buyukkale (4884889), Nilgun Koksal (6817937)   +20 more
core   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

PresenceAbsence: An R Package for Presence Absence Analysis [PDF]

The PresenceAbsence package for R provides a set of functions useful when evaluating the results of presence-absence analysis, for example, models of species distribution or the analysis of diagnostic tests.
Elizabeth A. Freeman, Gretchen Moisen
core  

ROC curve for GW.

, 2019
ROC curve for GW.
Kurthan Mert (6817961), Canan Aygun (6817946), Tulin Gokmen (6817964), Sezin Unal (6817955), Ugur Kayacan (6817931), Barıs Akcan (6817967), Yalcın Celik (6817928), Umut Zubarioglu (6817952), Mehmet Satar (6817940), Servet Ozkiraz (6817949), Begum Atasay (4884871), Hatice Turgut (6817958), Hilal Ozkan (6817934), Gaffari Tunc (4884895), Emel Okulu (4884880), Saadet Arsan (4884892), Mustafa Akcali (6817943), Omer Erdeve (4884868), Merih Cetinkaya (734526), Gokhan Buyukkale (4884889), Nilgun Koksal (6817937)   +20 more
core   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

ESTIMATING THE ROC CURVE AND ITS SIGNIFICANCE FOR CLASSIFICATION MODELS’ ASSESSMENT

Quantitative Methods in Economics, 2014
Article presents a ROC (receiver operating characteristic) curve and its application for classification models’ assessment. ROC curve, along with area under the receiver operating characteristic (AUC) is frequently used as a measure for the diagnostics ...
Ryszard Szupiluk, Krzysztof Gajowniczek, Tomasz Ząbkowski   +2 more
doaj