Biostatistics and Epidemiology for the Toxicologist: Rock the ROC Curve. [PDF]
J Med Toxicol, 2022 Trebach J, Su MK.
europepmc +1 more source
Advanced Science, EarlyView.Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen +8 more
wiley +1 more source
Nonparametric bootstrap methods for interval estimation of the area under the ROC curve with correlated diagnostic test data: application to whole-virus ELISA testing in swine. [PDF]
Front Vet Sci, 2023 Pang J +6 more
europepmc +1 more source
Advanced Science, EarlyView.RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu +7 more
wiley +1 more source
Estimating the area under the ROC curve when transporting a prediction model to a target population. [PDF]
Biometrics, 2023 Li B +3 more
europepmc +1 more source
Adjusted empirical likelihood estimation of the youden index and associated threshold for the bigamia model [PDF]
The Youden index is a widely used measure in the framework of medical diagnostic, where the effectiveness of a biomarker (screening marker or predictor) for classifying a disease status is studied.
Emilio Leton, Elisa M. Molanes
core
Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
Advanced Science, EarlyView.MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
wiley +1 more source
Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity
Advanced Science, EarlyView.Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang +12 more
wiley +1 more source
The relationship between nonsystematic delay discounting and low-quality survey responses in a sample of smokers: ROC curve analysis. [PDF]
Exp Clin Psychopharmacol, 2023 Yeh YH +3 more
europepmc +1 more source
Compact Tabletop Magnetic Resonance Elastography for Mapping Soft Tissue Viscoelasticity
Advanced Science, EarlyView.This work introduces a compact, low‐cost tabletop magnetic resonance elastography platform for high‐resolution viscoelastic mapping in soft‐tissue specimens. Using this method in human colorectal liver metastases, we demonstrate fully automated biomechanical profiling of treatment response and show that heterogeneity‐based metrics outperform ...
Weijie Zhao +19 more
wiley +1 more source