Results 231 to 240 of about 2,525,063 (363)

Transfer Learning and Permutation‐Invariance Improving Predicting Genome‐Wide, Cell‐Specific and Directional Interventions Effects of Complex Systems

open access: yesAdvanced Science, EarlyView.
SETComp, a transfer learning model based on permutation‐invariance, is pre‐trained on single‐compound intervention data and fine‐tuned on complex system (e.g., natural products) data. The model achieves up to 93.86% accuracy on complex system‐cell‐gene association predictions, outperforming the baseline by up to 27.59%.
Boyang Wang   +4 more
wiley   +1 more source

A Field‐Deployable RotEx‐LAMP‐LFA Platform for Molecular Triage of HPV‐Driven Oncogenesis

open access: yesAdvanced Science, EarlyView.
This study presents RotEx‐LAMP‐LFA, a fully integrated, battery‐powered, low‐cost point‐of‐care device for rapid cervical cancer risk detection based on HPV16/18 E6/E7 mRNA. Clinically validated, the system demonstrated high sensitivity and specificity, and showed full concordance between self‐collected and clinician‐collected samples, offering a ...
Yuan Gao   +10 more
wiley   +1 more source

Targeted Degradation of sGRP78 Alleviates the Immunosuppressive Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
Soluble GRP78 (sGRP78) is identified as a novel tumor‐derived soluble factor that induces regulatory T cells (Treg). sGRP78 serves as an excellent serological biomarker for predicting the efficacy of neoadjuvant therapy in breast cancer patients. sGRP78 specifically binds to B cells, inducing the expression of IL‐10 and PD‐L1, thereby promoting Treg ...
Zhenghao Wu   +10 more
wiley   +1 more source

ROC curve analysis: a useful statistic multi-tool in the research of nephrology. [PDF]

open access: yesInt Urol Nephrol
Roumeliotis S   +8 more
europepmc   +1 more source

A Floating‐Gate Photoelectric Synaptic Transistor Utilizing BP/POx/WSe2 Heterostructure for Neuromorphic Visual Processing

open access: yesAdvanced Science, EarlyView.
In this paper, a novel floating gate transistor (BP/POx/WSe2) is developed, which enables rich synaptic functionality under optoelectronic conditions and can mimic human visual memory. By introducing a two‐path convolutional neural network that synergistically fuses optical and electronic inputs, it can achieve efficient feature extraction and weight ...
Yuxuan Zeng   +13 more
wiley   +1 more source

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