Results 111 to 120 of about 287,298 (306)

Beyond the ROC Curve: Activity Monitoring to Evaluate Deep Learning Models in Clinical Settings

Applied Medical Informatics
We evaluated ‘VITALCARE-SEPS’, a deep learning model for sepsis prediction, using the activity monitoring operator characteristics curve with two different scoring algorithms.
Hyunwoo CHOO, Kyung Hyun LEE, Sungsoo HONG, Sungjun HONG, Ki-Byung LEE, Chang Youl LEE   +5 more
doaj  

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Receiver operating characteristic (ROC) curve for whole cohort.

, 2014
Discriminatory ability for death at one, two, and three years, evaluated by receiver operating characteristic (ROC) curve area, for Okuda, CLIP, BCLC and JIS scores for whole cohort.
Mohamed Saad Hashim (531752), Imam Waked (531753), Asmaa Ibrahim Gomaa (531751)   +2 more
core   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

ROC (receiver operating characteristic) analysis.

, 2015
1 = ocular residual astigmatism; 2 = Area under the curve; 3 = Spherical Equivalent; 4 = P value
Gisbert Richard (71493), Andreas Frings (703734), Vasyl Druchkiv (723867), Toam Katz (723868), Johannes Steinberg (723866), Stephan J. Linke (703733), Christos Skevas (673410)   +6 more
core   +1 more source

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

Advanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang, Yizhong Liang, Manan Sulaiman, Jiaqi Du, Ming Jiang, Zhihua Wang, Xu Yu, Li Xu   +7 more
wiley   +1 more source

Estimating the Area under a Receiver Operating Characteristic Curve For Repeated Measures Design

The receiver operating characteristic (ROC) curve is widely used for diagnosing as well as for judging the discrimination ability of different statistical models.
Honghu Liu, Tongtong Wu
core  

Receiver operating characteristic (ROC) curve for WBC and CRP.

, 2016
Receiver operating characteristic (ROC) curve for WBC (AUC: 0.728, 95% CI: 0.473–0.983, p = 0.098) and CRP in prediction the presence of acute appendicitis (AUC: 0.316, 95% CI: 0.033–0.593, p = 0.181).
Hubert Zirngibl (3608042), Valerie Orth (280906), Daniel Gödde (3608039), Peter C. Ambe (3608045)   +3 more
core   +1 more source

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

Advanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu   +14 more
wiley   +1 more source