Results 31 to 40 of about 1,504,519 (328)

Using a high-pressure water jet-assisted tunnel boring machine to break rock

Advances in Mechanical Engineering, 2020
The concept of tunnel boring machine (TBM) disc cutter rock breaking coupled with high-pressure water jets has been proposed to overcome the difficulties that occur when TBMs encounter extremely hard rocks.
Jinliang Zhang, Yongchang Li, Yuansheng Zhang, Fengwei Yang, Chao Liang, Shunhui Tan   +5 more
doaj   +1 more source

Rock breaking methods to replace blasting

IOP Conference Series: Materials Science and Engineering, 2018
The method of breaking rock by blasting has a high efficiency and the cost is relatively low, but the associated vibration, flyrock, production of toxic gases since the 1970's, the Western developed countries began to study the safety of breaking rock. This paper introduces different methods and their progress to safely break rock.
Huisheng Zhou, Xinghua Xie, Yuqing Feng
openaire   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Numerical Simulation of Rotary Impact Rock-Breaking Process of a Full-Size Drill Bit

Shiyou jixie, 2023
As the key fundamental aspect of rotary impact drilling technology, the mechanism of rock breaking has not been well demonstrated, which limits the application of this technology.To illustrate the rotary impact rock-breaking process, the numerical ...
Yan Yan, Han Lihong, Liu Yonghong, Yang Shangyu, Cao Jing, Mou Yisheng   +5 more
doaj  

Experimental Studies of Electrical Fields on a Breaking Rock Sample [PDF]

, 2001
When a rock sample is pressed by a force, the pressure on the crystal lattice generates an electrical field around the quart grains due to the piezoelectric effect.
Marone, Chris J., Morgan, Frank Dale, Toksoz, M. Nafi, Zhu, Zhenya   +3 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Numerical Simulation Study on Characteristics of Tight Hard Sand Broken by Axe-shaped PDC Cutter

Shiyou jixie, 2021
The study on the specific rock breaking mechanism of axe-shaped PDC cutter in the existing literatures is relatively less, the rock breaking characteristic test data are mostly for field application data, and there is short of theoretical basis of tooth ...
Zhao Runqi, Chen Zhenliang, Shi Huaizhong, He Wenhao, Shi Xingxing, Chen Han   +5 more
doaj  

Numerical study on the rock breaking mechanism of high-pressure water jet-assisted TBM digging technique based on 2D-DEM modelling

Frontiers in Earth Science, 2023
In order to improve the digging efficiency of tunnel boring machine (TBM) in high-strength and highly abrasive formations, high-pressure water jet-assisted tunnel boring machine rock breaking technology has been developed and applied in steps.
Yalong Jiang, J. Zeng, Liujie Jing, Changjie Xu, Fuyang Xiong   +4 more
semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Experimental research and energy analysis of a new type of dry ice powder pneumatic rock breaking technology

International Journal of Mining Science and Technology, 2023
When the traditional drill and blast method is applied to rock crushing projects, it has strong vibration, loud noise and dust pollution, so it cannot be used in densely populated areas such as urban public works.
Xiaofei Wang, Shaobin Hu, Enyuan Wang, Qiang Zhang, Bing Liu   +4 more
doaj   +1 more source