Results 221 to 230 of about 839,776 (287)

Molecular characterization in elite rock climbers: insights from multi-omics analysis. [PDF]

BMC Genomics
Liang R, Li J, Cao L, Wang C, Zhang S, Ye X.   +5 more
europepmc   +1 more source

Magnetoelastic Cell Monitoring System for Evaluating the Effects of Surface Chemistry on the Performance of Mesenchymal Stem Cell Growth

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The recent clinical adoption of cell therapies has increased the need for more efficient, robust, and reproducible manufacturing technologies. Human mesenchymal stromal cells (hMSCs), a major component of the cell and immunotherapeutic market, remain challenging to manufacture at scale because they require surface attachment and are highly ...
William S. Skinner, Carolina Rivera‐Crespo, Eyerusalem A. Gebreyesus, Said Cifuentes, Samantha Tan, Tristen Douglas, Maribella Domenech‐Garcia, Keat Ghee Ong   +7 more
wiley   +1 more source

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

Viscoelastic hydrogel potentiates cancer cell stemness and drug resistance through Piezo1‐dependent mechanotransduction

BMEMat, EarlyView.
The effects of matrix dynamics on cancer progression remain unclear. Herein, we fabricated a tunable dynamic hydrogel via reversible host–guest crosslinking and demonstrated that high matrix dynamics activate Piezo1 and its downstream PI3K/AKT and Wnt/β‐catenin signaling pathways, thereby enhancing cancer spheroid assembly, elevating cancer stemness ...
Yi Liu, Huiyao Deng, Hanlei Zhang, Chutian Huang, Huolun Feng, Xiayi Xu, Heemin Kang, Meiling Zhu, Liming Bian, Kunyu Zhang   +9 more
wiley   +1 more source

Nutrition prescription for climbing athletes on rock or artificial surfaces: are we guessing? [PDF]

Front Sports Act Living
Joubert L, Michael M, Nugent C, Chmielewska A.   +3 more
europepmc   +1 more source

Ant Diversity of the Xisha Islands: Community Structure, Exotic Species Colonization, and Ecological Functions in a Tropical Coral Archipelago

Biological Diversity, EarlyView.
The first inventory of ants from the Xisha Islands of the South China Sea was compiled, revealing 21 species: 70% native and 30% exotic. Anthropogenic disturbance primarily drove exotic colonization, whereas island area showed weak positive effects on species richness. Most ants were omnivorous, with key mutualistic and seed‐dispersal roles.
Hua‐Yan Chen, Zhi‐Xuan Liu, Zheng‐Hui Xu, Rui‐Chong Wang, Shi‐Xiao Luo   +4 more
wiley   +1 more source

The convergent evolution of the pelvic suction cup: A unique key innovation in spiny-finned fishes. [PDF]

Sci Adv
McFarland EP, Medeiros APM, Pedraza-Marrón CDR, Hughes LC, Pirro S, Santos EC, Santaquiteria A, White WT, Miya M, Ortí G, Linley TD, Baldwin CC, Orr JW, Arcila D, Tornabene LM, Betancur-R R.   +15 more
europepmc   +1 more source

Above the Hum. [PDF]

J Grad Med Educ
Abioye OF.
europepmc   +1 more source