Results 181 to 190 of about 382,665 (308)

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

open access: yesAdvanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li   +8 more
wiley   +1 more source

Block identification and stability analysis of underground stope with multi-working face. [PDF]

open access: yesPLoS One
Zhang M   +7 more
europepmc   +1 more source

Dynamic Etching‐Induced Cl‐Terminated Ti3C2Clx/Ti3ZnC2 Heterostructure for Ammonia Electrosynthesis and Zinc‐Nitrogen Batteries

open access: yesAdvanced Science, EarlyView.
A stable Ti3C2Clx/Ti3ZnC2 heterostructure, fabricated by dynamic etching, exhibits outstanding electrocatalytic NRR activity (NH3 yield: 20.1 µg h−1 mg−1, FE: 38.1%) in alkaline media. The corresponding Zn‐N2 battery achieves a peak power density of 36.5 µW cm−2 and an NH3 yield of 13.1 µg h−1 mg−1, providing an advanced strategy for NH3 and ...
Yu Wang   +9 more
wiley   +1 more source

The effects of gravity on rock fractures caused by PDC bits. [PDF]

open access: yesSci Rep
Zhang Q   +5 more
europepmc   +1 more source

A Dynamic 3D Human Liver Sinusoid Model for Mechanistic Interrogation of Fontan‐Associated Liver Disease

open access: yesAdvanced Science, EarlyView.
This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab   +14 more
wiley   +1 more source

MGDP: Mastering a Generalized Depth Perception Model for Quadruped Locomotion

open access: yesAdvanced Science, EarlyView.
ABSTRACT Perception‐based Deep Reinforcement Learning (DRL) controllers demonstrate impressive performance on challenging terrains. However, existing controllers still face core limitations, struggling to achieve both terrain generality and platform transferability, and are constrained by high computational overhead and sensitivity to sensor noise.
Yinzhao Dong   +9 more
wiley   +1 more source

The Choice of Drilling Pipes [PDF]

open access: yes, 2017
Mahoukou, Prince   +2 more
core  

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