Results 81 to 90 of about 1,056,070 (342)

Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging

Advanced Science, EarlyView.
Cell death is important in both the development and treatment of cancer. In this study, it is demonstrated for the first time that a specific measurement of the transmembrane water exchange rate using magnetic resonance imaging can be used as an early marker of cell death in mammalian cells, in animals and in human patients. Abstract Cell death plays a
Athanasia Kaika, Luca Nagel, Ulrike Höckendorf, Bangwen Xie, Geoffrey J. Topping, Mathias Schillmaier, Irina Beer, Frits H. A. van Heijster, Julian Rauch, Tristan A. Kuder, Sandra Sühnel, Bernd Erber, Christian Lohrmann, Simone Ballke, Thomas Metzler, Katja Steiger, Philipp J. Jost, Natalia P. Ivleva, Philipp Paprottka, Jonathan Nadjiri, Kevin M. Brindle, Wolfgang A. Weber, Franz Schilling   +22 more
wiley   +1 more source

3D Numerical Simulation and Experiment Validation of Dynamic Damage Characteristics of Anisotropic Shale for Percussive-Rotary Drilling with a Full-Scale PDC Bit

Energies, 2018
The lower rate of penetration (ROP) is one of the key technical difficulties during drilling of shale reservoirs. Percussive-rotary drilling (PRD) is crucial for increasing ROP.
Guangjian Dong, Ping Chen
doaj   +1 more source

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

Advanced Science, EarlyView.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin, Koji Nagaoka, Myrofora Panagi, Akihiro Hosoi, Fotios Mpkeris, Pengwen Chen, Thahomina T. Khan, Margaret R. Martin, Changbo Sun, Chrysovalantis Voutouri, Maria Louca, Panagiotis Papageorgis, Akira Sumiyoshi, Nobuhiro Nitta, Kazuyoshi Takeda, Ichio Aoki, Kazunori Kataoka, Triantafyllos Stylianopoulos, Kazuhiro Kakimi, Horacio Cabral   +19 more
wiley   +1 more source

Impact of Rock Cuttings on Downhole Fluid Movement in Polycrystalline Diamond Compact (PDC) Bits, Computational Fluid Dynamics, Simulation, and Optimization of Hydraulic Structures

Fluids
The flow occurring at the bottom of a polycrystalline diamond compact (PDC) drill bit involves a complex process made up of drilling fluid and the drilled rock cuttings.
Lihong Wei, Jaime Honra
doaj   +1 more source

Gallium Nitride Semiconductor Resonant Tunneling Transistor

Advanced Science, EarlyView.
Three‐terminal GaN semiconductor resonant tunneling transistors (RTTs), which comprise an double‐barrier AlN/GaN/AlN resonant tunneling diode integrated with a GaN high‐electron‐mobility transistor (HEMT) through epitaxial growth in series and parallel configuraions, respectively.
Fang Liu, JunShuai Xue, GuanLin Wu, JinYuan Yuan, JiaJia Yao, RenJie Liu, Zhuang Guo, ZeHui Li, HaoRan Hu, WenBo Sun, Cheng Zhao, ChenKai Zhang, XinYan Liu, Kai Zhang, JinCheng Zhang, Yue Hao   +15 more
wiley   +1 more source

Integrated geo-ecological assessment of drill cuttings and approaches to their disposal

RUDN Journal of Ecology and Life Safety
The study discusses the chemical properties of rock and drill cuttings. Drill cuttings have a negative impact on the components of the natural environment: soil cover, atmospheric air, groundwater. The purpose of the research was a comprehensive study of
Elena V. Gaevaya
doaj   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Structural heterogeneity and permeability in faulted eolian sandstone: Implications for subsurface modeling of faults [PDF]

, 2002
We determined the structure and permeability variations of a 4 km-long normal fault by integrating surface mapping with data from five boreholes drilled through the fault (borehole to tens of meters scale).
Evans, J.P., Forster, C.B., Robeson, K.R., Shipton, Z.K., Snelgrove, S.   +4 more
core  

Design of cavity drill bit while drilling for gas drainage of crossing borehole

Gong-kuang zidonghua, 2019
In order to improve gas drainage effect of crossing borehole, cavity drilling technology is often used to increase part borehole diameter of coal seam section, which avoids invalid footage of hole section in rock layer.
GAO Xiaoliang, ZHANG Xianzhen, LU Qianhai   +2 more
doaj   +1 more source

Study of sample drilling techniques for Mars sample return missions [PDF]

To demonstrate the feasibility of acquiring various surface samples for a Mars sample return mission the following tasks were performed: (1) design of a Mars rover-mounted drill system capable of acquiring crystalline rock cores; prediction of ...
Harris, P. T., Mitchell, D. C.
core   +1 more source