Results 41 to 50 of about 111,840 (308)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Research on Damage Evolution Mechanism of Layered Rock Mass under Blasting Load

Buildings
Rock mass consists of many discontinuities, such as faults, joints, etc., and layered joints are a common kind of rock mass structure. The joints affect the stress wave propagation, and blasting is an economical and efficient rock fragmentation method ...
Lixiang Xie, Jiahao Zhang, Dongyu Yang, Yanjun Qi, Linjun Wu, Hongyun Chen   +5 more
doaj   +1 more source

Development of a damage rheological model and its application in the analysis of mechanical properties of jointed rock masses

Energy Science & Engineering, 2019
Fossil fuel resources (eg, coal, oil, and natural gas) exist in underground reservoirs, where discontinuities are widespread and influence the stability of rock structures.
Wendong Yang, Guangyu Luo, Kang Duan, Wenjun Jing, Lianzhen Zhang, Shugang Wang, Yan Zhao   +6 more
doaj   +1 more source

Shear creep characteristics and constitutive model of hidden non-persistent joints

Yantu gongcheng xuebao, 2019
The joints control the boundary of the rock slope instability. A large number of joints in the natural world are not completely persistent, and are hidden inside the slope.
LI Ren-jie , JI Feng , FENG Wen-kai , WANG Dong-po , ZHANG Jin-ming
doaj   +1 more source

Implementation of probabilistic approach to rock mass strength estimation while excavating through fault zones [PDF]

, 2019
Purpose. The paper addresses the rock mass state estimation while excavating a cross-heading through the area of regional fault “Bohdanivskyi” based on probabilistic approach to assessing the rock strength. Methods.
Babets, D, Cabana, E.C., Kravchenko, K, Sdvyzhkova, O, Shashenko, O   +4 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Influencing Factors of Shear Instability Characteristics of Rock Joints: Experimental and Theoretical Study

Applied Sciences
To investigate the influencing factors of the shear failure behavior of rock joints, especially the shear instability characteristics, direct shear tests were performed on marble joints with various grain sizes under different constant normal loads (CNLs)
Hangyu Dong, Baohua Guo, Qing Ma, Kai Si, Hongjian Wang   +4 more
doaj   +1 more source

Research on direct shear behaviour and fracture patterns of 3D-printed complex jointed rock models

Rock and Soil Mechanics, 2020
Geometry and mechanical characteristics of joints are key factors affecting the shear behaviors and fracture patterns of jointed rock mass. Using 3D printing technique, experimental jointed rock specimens containing rough joints with varied joint ...
WANG Pei-tao, HUANG Zheng-jun, REN Fen-hua, ZHANG Liang, CAI Mei-feng   +4 more
doaj   +1 more source

Simulating spatial and temporal evolution of multiple wing cracks around faults in crystalline basement rocks [PDF]

, 2007
Fault zones are structurally highly spatially heterogeneous and hence extremely complex. Observations of fluid flow through fault zones over several scales show that this structural complexity is reflected in the hydrogeological properties of faults ...
Anderson, Aydin, Burgmann, Byerlee, Caine, COMSOL, Cruikshank, d'Alessio, d'Alessio, Dalguer, do Nascimento, Du, Du, Evans, Evans, Evans, Evans, Fairley, Galli, Jonathan P. Willson, Lim, Lockner, Losh, Losh, Martel, Martel, Martin, Morrow, Niemeijer, Pollard, Rebecca J. Lunn, Segall, Shen, Tang, Turcotte, Vermilye, Wibberley, Willson, Yamashita, Zoe K. Shipton   +39 more
core   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, in collaboration with the Consensus Expert Panel (CEP) members, G. Alden Adkins, Brittany Adler, Hossein Ansari, Senada Arabelovic, Alan Baer, Denis Balaban, Shamik Bhattacharyya, Evelyn Bromet, Krishna Chaganti, Kamal Chemali, Melissa Cortez, Schartess Culpepper, Paul Dellaripa, Dana Direnzo, Daniel El Bogdadi, Robert Fearon, Mehrnez Fischbach, Judi Furlong, Christopher Gibbons, Rachael Gordon, Thomas Grader Beck, Syed Haider, Larry Hollenbeck, Chadwick R. Johr, Stuart S. Kassan, Brian King, Octavia Kincaid, Eugene Kissin, Vasileios Kyttaris, Lindsay Lally, Brandon M. Law, Janet Lewis, Scott M. Lieberman, Amanda Lusa, Joseph Lutt, Rashmi Maganti, Arthur M. Mandelin, Sara McCoy, Kerry Neall, Timothy Niewold, Anne Louise Oaklander, Ruben A. Peredo‐Wende, Lynn Petruzzi, Mark A. Porter, Guada Respicio Duque, Tania Reyna, Nathaniel M. Robbins, Elliot D. Rosenstein, Laura Rosow, Breanna Ruthrauff, Amit Sachdev, Nora Sandorfi, Sarah Schafer, Elena Schiopu, Chokkalingam Siva, Daniel Small, Sara M. Stern, Lauren Stiles, Susan Stoddard, Jinny Tavee, Donald Thomas, Edward L. Treadwell, Nagagopal Venna, Steven Vernino, Frederick B. Vivino, Brittany Weber, Sepideh Yadollahi, Huiying Yu, Scott Zashin   +88 more
wiley   +1 more source