Results 201 to 210 of about 868,049 (299)

Fastening in Rock Mass-Structural Design of Shallow Embedded Anchors in Inhomogeneous Substrate. [PDF]

Materials (Basel)
Lamplmair-Irsigler S, Zeman O, Stierschneider E, Voit K.   +3 more
europepmc   +1 more source

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Quantitative analysis of the performance improvement of the surrounding rock mass by applying a prestressed bolt system. [PDF]

Sci Rep
Yang X, Xue H, Guo J, Zhang M.
europepmc   +1 more source

Bioinspired Adaptive Leg‐Claw Enables Robust Perching and Grasping for UAVs

Advanced Science, EarlyView.
Inspired by owl limb morphology and bat roosting behavior, this study presents a bioinspired adaptive leg‐claw mechanism that enables UAVs to perform robust and versatile perching and grasping. The design integrates a four‐link tibial structure, tension‐driven deformable feet, and active control, enabling stable perching on various branches and ...
Tianyu Cheng, Shaokun Wang, Jiehan Zou, Guiwen Shi, Zhongxue Gan, I‐Ming Chen, Guo‐Niu Zhu   +6 more
wiley   +1 more source

Dynamic numerical simulation analysis of rockburst grade evaluation based on rock mass strength. [PDF]

Sci Rep
Wang Y, Xu J, Zhang Y.
europepmc   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

Advanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong, Jingyi Lu, Haopeng Li, Jun Zhong, Xiaobei Luo, Yiyi Hu, Xianfei Wang, Pengfei Wang, Yanning Zhang, Zhenjiang Wang, Qiuhua Lai, Zhenyu Chen, Wenting Mi, Wang Tin San‐to, Weize Li, Shuping Tan, Qihong Cheng, Ruijia Li, Yida Nie, Side Liu, Bing Huang, Zelong Han   +21 more
wiley   +1 more source

Study on the mechanical properties and failure mechanism of a multi-lithologic layered rock mass. [PDF]

Heliyon
Zeng B, Qiu G, Huang H, Guo Y, Xu E, Gui J, Li J.   +6 more
europepmc   +1 more source

Circular Potential of Lithium‐Ion Battery Recycling Slags: Quantifying Microstructure and Elemental Distribution for a Holistic Valorization

Advanced Science, EarlyView.
A lithium‐bearing slag is investigated with the goal of holistic valorization. The present β‐eucryptite (LiAlSiO4) exhibits a high lithium content and low levels of impurities. The spinel contains most of the chromium and vanadium, representing additional valorization opportunities.
Peter Cornelius Gantz, Charlize Alexia Senkyr, Rüdiger Kilian, Andreas Neumann, Maximilian Korges, Daniel A. Frick, Hans Roggendorf, Ralf Wehrspohn, Stefan Stöber, Christiane Stephan‐Scherb   +9 more
wiley   +1 more source

Effect of thickness and inclination angle of weakly cemented interlayer on fracture development and fracture energy evolution of rock mass. [PDF]

Sci Rep
Qi C, Wang B, Mao Y, Li Z, Qi T, Hu G, Qin W, Zhu J.   +7 more
europepmc   +1 more source

Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models

Advanced Science, EarlyView.
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka, Yuhei Higashi, Suguru Saito, Solmaz Pourgonabadi, Honami Honjoh, Sho Ishigaki, Peter C. Harris, Lisa M. Satlin, Michifumi Yamashita, Ryuji Morizane   +9 more
wiley   +1 more source