Results 271 to 280 of about 255,885 (342)

Quantitative characterization and optimization of fracability in continental shale reservoirs. [PDF]

Sci Rep
Cheng L, Gao H, Li H.
europepmc   +1 more source

Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine

Advanced Science, EarlyView.
This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan, Beibei Xu, Jenna McCormack, XuHai Huang, Jingzhe Ma, Thomas Marshall, Yacong Sun, Hardeep Singh, Alyssa Fanelli, Gauri Kulkarni, Ji Hye Seo, Paige Gilbride, Bing Wei, Bo Wang, Yanyan Liu, Fei Ma, Lin Zhou, Shuyang Wang, Xiaohua Qian, Zhiyong Xie, Polina Golland, Longlong Si, Yu Shrike Zhang, Xin Xie, Haiqing Bai   +24 more
wiley   +1 more source

Small-scale experimental and numerical simulation of blasting in jointed rock-like materials under varied joint and explosive conditions. [PDF]

PLoS One
Cui X, Zhao M, Yu H, Zhou J.
europepmc   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Study on roof partition fracture based on dominant primary fracture. [PDF]

Sci Rep
Xia W, Qiang L, Yongkai Z, Yuqi R, Hao Y, Weijie W, Yuesong T.   +6 more
europepmc   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Effect of thickness ratio on uniaxial mechanical behavior of soft-hard composite rock masses: experimental analysis and modeling. [PDF]

Sci Rep
Li JH, Li YL, Wang P, Liu WX, Yang Y.
europepmc   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

The effects of gravity on rock fractures caused by PDC bits. [PDF]

Sci Rep
Zhang Q, Zhou Y, Su Y, Gong T, Li D, Tang Y.   +5 more
europepmc   +1 more source

Achieving Fast Charging and Superior Cycling Stability Single‐Crystal Ni‐Rich Cathodes by Ultrafast Aqueous Washing

Advanced Science, EarlyView.
Prolonged water washing severely damages the surface layered structure of single‐crystal Ni‐rich cathodes, forming a thick rock‐salt barrier. In contrast, our 3‐min ultrafast washing removes residual lithium while confining surface reconstruction to an ultrathin 2–4 nm layer, thereby unlocking excellent fast‐charging and cycling stability.
Kaixin Liu, Jia Yang, Huaping Wang, Yongtao Tan, Dongdong Fan, Yongjian Cui, YunJian Liu, Xiaoyan Li, Hailong Wang   +8 more
wiley   +1 more source