Results 31 to 40 of about 1,407,177 (296)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Particle Flow Analysis of Macroscopic and Mesoscopic Failure Process of Salt Rock under High Temperature and Triaxial Stress

Geofluids, 2021
In order to reveal the mechanism of thermal-induced deformation and fracture development of salt rock under high temperature, the particle flow program PFC2D was used to study the triaxial compression failure process of salt rocks under different ...
Haoran Li, Ziheng Wang, Dekang Li, Yajun Zhang   +3 more
doaj   +1 more source

COMPARISON OF GEO-MECHANICAL PROPERTIES OF WHITE ROCK SALT AND PINK ROCK SALT IN KŁODAWA SALT DIAPIR [PDF]

Studia Geotechnica et Mechanica, 2013
Abstract Within the boundaries of the Salt Mine “Kłodawa”, rock-salts and potassium-magnesium salts occur at different stratigraphic levels. The present article introduces strength-strain properties of white rock salt, building the nucleus of northeastern edge anticline, and pink rock salt that belongs to the series of youngest rock salt.
Malwina Kolano, Danuta Flisiak
openaire   +1 more source

High‐Entropy Alloy Interlayers Toward Advanced Joining for High‐Performance Structural Applications: Current Progress and Emerging Challenges

Advanced Engineering Materials, EarlyView.
HEA interlayers offer a versatile route for joining high‐performance structural materials. Their compositional and structural design regulates interfacial reactions, suppresses brittle IMCs, and improves metallurgical bonding. Sandwich interlayers further integrate defect healing with precipitation strengthening, enabling improved strength–ductility ...
Lin Yuan, Jiafen Song, Jinglong Li, Jiangtao Xiong, Tao Yang   +4 more
wiley   +1 more source

A Multi‐Scale Machine Learning Framework for the Inverse Design of High Entropy Alloys

Advanced Engineering Materials, EarlyView.
High‐entropy alloys offer vast potential for various applications, including electrocatalysis; however, their compositional complexity challenges conventional screening. We introduce an inverse‐design framework combining two neural networks to determine optimal compositions and reconstruct nanoparticle geometry from targeted properties and conventional
Mikael Takoutsin, Marta Campolucci, Nicolas de Andrade Ishiki, Nathan Mirgot, Nadir Zhamantay, Frédéric Kanoufi, Jennifer Peron, Jean Charlety, Emiliano Fonda, Valérie Briois, Marco Faustini, Maria‐Letizia De Marco, Christine Goyhenex, Ovidiu Ersen, Hervé Bulou   +14 more
wiley   +1 more source

Impurity Effects on the Mechanical Properties and Permeability Characteristics of Salt Rock

Energies, 2020
Impure salt rock strata are extensively distributed in China, giving them great significance in the study of the physical properties of impure salt rock for the construction of underground gas storage in salt mines.
Qiangxing Zhang, Jianfeng Liu, Lu Wang, Min Luo, Hejuan Liu, Huining Xu, Hang Zou   +6 more
doaj   +1 more source

The Cenozoic salt diapir near Eyvanekey and Garmsar, Iran : new insights from structural investigations and analogue modeling [PDF]

, 2011
The Alborz Mountains are forming a ~100 km wide, E-W trending mountain chain where individual summits are up to 5000 m in elevation. The Alborz Mountains range are part of the Alpine orogen and are straddling a 2000 km wide area S of the Caspian Sea. The
Baikpour, Shahram
core  

Electrospun Wood‐Derived Biopolymers as Electrodes in Electrochemical Energy Storage Technologies

Advanced Functional Materials, EarlyView.
Electrospinning transforms wood‐derived cellulose and lignin into architecturally defined, binder‐free carbon electrodes with tuneable porosity and functionality. This review shows how fibre design enables decoupled charge and mass transport, enhancing performance across battery systems, while identifying key challenges in spinnability, scalability ...
Michael W. Thielke, Hattie R. Chisnall, Jesus Vazquez Chavez, Ana B. Jorge Sobrido   +3 more
wiley   +1 more source

Functionalizing Micro‐to‐Mesoscopic Electrode Architectures for Regulating Electron Transfer Behaviors in Electrocatalysis

Advanced Functional Materials, EarlyView.
A systematic review is conducted to assess the influence of electrode architecture across micro‐ to mesoscopic length scales on electron‐transfer pathways in electrocatalysis. We discuss the structure‐activity relationships in electrocatalytic applications, including resource recovery and environmental remediation, and provide cost‐effective, efficient
Manshu Zhao, Jiaojiao Zhang, Shideng Yuan, Xinmeng Yu, Keming Wan, Xiaoguang Duan, Zhining Wang   +6 more
wiley   +1 more source

Methodology for determining occluded gas contents in domal rock salt [PDF]

"The Bureau of Mines has developed two experimental designs for determining the volumes and relative proportions of the various gas species, particularly methane (ch4), occluded in rock salt.

core   +2 more sources