Results 161 to 170 of about 764,678 (283)

Multi-scale reservoir characterization of pre-rift reservoirs in the October field, Gulf of Suez using integrated seismic, well logs, and core data. [PDF]

Sci Rep
Ghaly M, Othman AAA, Elkhawaga M, Mostafa T.   +3 more
europepmc   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

Characterizing low-permeable shales using Rock-Eval pyrolysis and nuclear magnetic resonance for reconstruction of fluid saturation model. [PDF]

Sci Rep
Mukhametdinova A, Markovic S, Maglevannaia P, Kozlova E, Kolomytsev A, Al-Shalabi EW, Cheremisin A, Spasennykh M.   +7 more
europepmc   +1 more source

2D Inorganic Electrides: Interstitial Electrons as Key Drivers of Multifunctional Properties and Applications

Advanced Science, EarlyView.
Eight AB‐type 2D inorganic electrides with negatively charged transition metals are theoretically designed. Their monolayers exhibit intrinsic magnetic ordering, rich topological phases, and ultralow work functions. Supported metal Ru on these 2D inorganic electrides effectively alleviates hydrogen poisoning and enables efficient ammonia synthesis ...
Qianwen Zhang, Xia Cheng, Zhenzhou Guo, Weiyao Jia, Ying Yang, Zhenxiang Cheng, Weizhen Meng   +6 more
wiley   +1 more source

Integrated dry hole, seismic, and structural analysis improves hydrocarbon exploration in the Egyptian Northern Red Sea basin. [PDF]

Sci Rep
Eid AM, Hassan M, Amer M, Mabrouk WM, Metwally A.   +4 more
europepmc   +1 more source

A Blood‐Derived Double‐Network Hydrogel with Robust Wet Adhesion for Keratinized Mucosa Regeneration via Neutrophil Phenotype Reprogramming and Mechanophysical Niche Modulation

Advanced Science, EarlyView.
The iPRF‐MA/Alg‐NHS/Lut@EGCG (PGAE) double‐network hydrogel achieves durable wet adhesion in the oral environment. It simultaneously reprograms neutrophils from NETosis to phagocytosis for biofilm clearance, and activates the FAK‐RhoA‐YAP mechanotransduction pathway in gingival fibroblasts to drive extracellular matrix remodeling, thereby promoting ...
Sicong Ren, Xinting Yang, Jingxia Chen, Yihan Wang, Jian Feng, Jing Zhou, Jiaxin Luo, Jingjie Zhai, Quan Lin, Yanmin Zhou   +9 more
wiley   +1 more source

Preformed donor-specific antibodies are associated with acute rejection and biliary complications after liver transplantation: A Swiss Transplant Cohort Study analysis. [PDF]

Liver Transpl
Vionnet J, Ferrari-Lacraz S, Hoessly LD, Mancarella A, Müller YD, Schaub S, Nilsson J, Wirthmüller U, Stampf S, Koller M, Mueller NJ, Amrari M, Manuel O, Golshayan D, Fraga M, Moradpour D, Goossens N, Magini G, Compagnon P, McLin V, Rock N, Wildhaber B, Kremer AE, Oberholzer J, Sousa Da Silva RX, Tinguely P, Kavaliukaite L, Berzigotti A, Banz V, Bernsmeier C, Dutkowski P, Semela D, Niemann M, Pantaleo G, Pascual M, Villard J, and the Swiss Transplant Cohort Study (STCS).   +36 more
europepmc   +1 more source

3D‐Mixer‐Assisted High‐Entropy Doping of LiNiO2 for Co‐Free Ni‐Rich Cathodes in Lithium‐Ion Batteries

Advanced Science, EarlyView.
High‐entropy doping of Co‐free Ni‐rich LiNiO2 cathodes is achieved through a scalable 3D mixing process. Multi‐element incorporation stabilizes the layered structure, alleviates Li/Ni disorder and electrode swelling, and enhances cycling stability. This approach underscores the potential of high‐entropy strategies to deliver structurally robust and ...
Seung Ri Kim, Thillai Govindaraja Senthamaraikannan, Jun Jae Myeong, Hyung Do Kim, Dong‐Hee Lim, Eun Mi Kim, Sang Mun Jeong   +6 more
wiley   +1 more source

Environmental reservoirs of carbapenem-resistant organisms in the intensive care unit: a multicenter longitudinal study in two middle-income country hospitals. [PDF]

Antimicrob Resist Infect Control
Fabre V, Robinson ML, Martino F, Monge R, Forastiero A, Corso A, Pasteran F, Karyakarte R, Randive B, Singh S, Naik M, Prasad HB, Schwab KJ, Simner PJ, Berman Y, Foy WI, Salinas AB, Gupta A, Lu J, Vasquez AM, Noble-Wang J, Moser KA, Perry-Dow KA, Patrick M, Rock C.   +24 more
europepmc   +1 more source

Quality Thresholds for Angiogenesis Under Acoustic Manipulation in Engineered Vascular Tissues

Advanced Science, EarlyView.
Defined biological and physical quality thresholds achieved through acoustic manipulation regulate cellular alignment and spatial organization, promoting self‐assembling vasculature, extracellular matrix deposition, and angiogenic responses, thereby establishing critical acoustic patterning requirements for engineered vascular tissue development in ...
Oscar O'Dwyer Lancaster‐Jones, Russell Quinn, Niloofar Khoshdel Rad, Kilian Paul, Andrea Frank, Daniela F. Duarte Campos   +5 more
wiley   +1 more source