Results 31 to 40 of about 764,678 (283)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The rock typing of complex clastic formation by means of computed tomography and nuclear magnetic resonance

Georesursy
This study provides a new rock-typing approach for low-resistive and low-permeable clastic rocks. The approach includes integrated interpretation of routine core analysis data with microstructural characteristics, acquired from computed tomography (CT ...
A. A. Tchistiakov, E. V. Shvalyuk, A. A. Kalugin   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

PREDIKSI PERMEABILITAS MENGGUNAKAN METODE LOG DAN PORE GEOMETRY STRUCTURE (PGS) PADA DAERAH CEKUNGAN JAWA BARAT UTARA

JGE, 2020
Determination of reservoir rock properties is very important to be able to understand the reservoir better. One of these rock properties is permeability. Permeability is the ability of a rock to pass fluid.
Ayu Yuliani, Ordas Dewanto, Karyanto Karyanto, Ade Yogi   +3 more
doaj   +1 more source

Irida: A machine learning based code for the automated derivation of site-specific rock type logs and their properties using Kimeleon colourlith image logs

Applied Computing and Geosciences, 2022
High resolution characterization of sub-surface geology is critical to improving the performance of reservoir models in fluid flow and reactive transport simulation studies in the fields of groundwater, CO2 geo-sequestration and oil and gas research. The
Achyut Mishra, Apoorv Jyoti, Ralf R. Haese   +2 more
doaj   +1 more source

“Rocking-Chair”-Type Metal Hybrid Supercapacitors [PDF]

ACS Applied Materials & Interfaces, 2016
Hybrid supercapacitors that follow a "rocking-chair"-type mechanism were developed by coupling divalent metal and activated carbon electrodes in nonaqueous electrolytes. Conventional supercapacitors require a large amount of electrolyte to provide a sufficient quantity of ions to the electrodes, due to their Daniell-type mechanism that depletes the ...
Yoo, Hyun Deog, Han, Sang-Don, Bayliss, Ryan D, Gewirth, Andrew A, Genorio, Bostjan, Rajput, Nav Nidhi, Persson, Kristin A, Burrell, Anthony K, Cabana, Jordi   +8 more
openaire   +3 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Integrating Rock Typing and Petrophysical Evaluations to Enhance Reservoir Characterization for Mishrif Formation in Garraf Oil Field

Iraqi Geological Journal
Accurate reservoir characterization is essential for successful hydrocarbon extraction, especially in complex fields such as the Garraf Oil Field.
Hayder Alrekabi, Omar Al-Fatlawi
doaj   +1 more source

Formation evaluation and rock type classification of Asmari Formation based on petrophysical- petrographic data: A case study in one of super fields in Iran southwest

Petroleum, 2023
The Oligo-Miocene Asmari Formation is one of the most important hydrocarbon reservoirs in the Middle East. The oilfield under study is one of the largest oilfields in the Zagros basin with the Asmari Formation being the major reservoir rock.
Raeza Mirzaee Mahmoodabadi, Sadegh Zahiri   +1 more
doaj   +1 more source