Results 61 to 70 of about 114,104 (197)

Educação e propaganda sanitárias: desdobramentos da formação de um sanitarista brasileiro na Fundação Rockefeller [PDF]

História, Ciências, Saúde: Manguinhos
Resumo O artigo discute a influência da formação de jovens sanitaristas na Fundação Rockefeller para as ações que desenvolveram nos cargos de chefia sanitária no Brasil. São apresentados os métodos de educação e propaganda sanitárias da instituição norte-
Ricardo dos Santos Batista
doaj   +2 more sources

17‐epi‐Melianodiol, a new protolimonoid from Melia azedarach fruits, exhibits larvicidal activity and is associated with oxidative imbalance and midgut epithelial damage in Aedes aegypti larvae

Pest Management Science, Volume 82, Issue 9, Page 9240-9248, September 2026.
The bio‐guided phytochemical study resulted in the new compound 17‐epi‐melianodiol. The compound eliminated 100% of Aedes aegypti larvae at 100 ppm, causing pronounced morphological changes, cuticular damage, and extensive vacuolization. Abstract BACKGROUND In Brazil, Aedes aegypti is the primary vector of arboviruses such as dengue, chikungunya ...
Kethleen Duarte Crespo Soares, Thalya Soares Ribeiro Nogueira, Maria Aparecida Aride Bertonceli, Renata Rodrigues da Silva Robaina, Leticia Oliveira da Rocha, Francisco José Alves Lemos, Kátia Valevski Sales Fernandes, Raimundo Braz‐Filho, Ivo José Curcino Vieira   +8 more
wiley   +1 more source

498 Bruton’s tyrosine kinase (BTK) inhibitors impede platelet aggregation but not adhesion to collagen.

Journal of Clinical and Translational Science
OBJECTIVES/GOALS: The research objectives of this project are to elucidate the effects of Bruton’s tyrosine kinase inhibitors (BTKi) of varying target specificity on platelet function with regard to platelet aggregation, adhesion, spreading, and ...
Thomas Kartika, Lorena Buitrago, Jihong Li, Barry S. Coller   +3 more
doaj   +1 more source

Mammalian miRNA curation through next-generation sequencing

Frontiers in Genetics, 2013
Characteristic small RNA biogenesis processing patterns are used for the discovery of novel microRNAs (miRNAs) from next-generation sequencing data. Here, we highlight and discuss key criteria for mammalian – specifically human – miRNA database curation ...
Miguel eBrown, Markus eHafner, Thalia eFarazi, Tom eTuschl   +3 more
doaj   +1 more source

Sex and Chronic Stress Alter the Distribution of Corticotropin‐Releasing Factor Receptor in Rat Hippocampus Following Oxycodone Conditioned Place Preference

Synapse, Volume 80, Issue 5, September 2026.
Chronic stress modifies the effect of oxycodone conditioned place preference (Oxy CPP) on corticotropin releasing factor 1 (CRFR1) subcellular distributions in hippocampal subregions. These stress‐ and oxycodone‐induced changes in CRFR1 density may influence sex differences in hippocampal learning and memory processes both at baseline and following Oxy
Dana N. Silberstein, Zoha Baig, Batsheva Rubin, Fangmin Yu, Joshua Kogan, Jason D. Gray, Yan Zhou, Teresa A. Milner   +7 more
wiley   +1 more source

Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures

Nature Communications, 2017
Understanding of the mycobacterial transcription system is useful to the development of therapeutics against tuberculosis infection. Here the authors present the crystal structure of a completeM. smegmatisRNA polymerase open promoter complex that reveals
Elizabeth A. Hubin, Mirjana Lilic, Seth A. Darst, Elizabeth A. Campbell   +3 more
doaj   +1 more source

Relationship of the chemokine, CXCL12, to effects of dietary fat on feeding-related behaviors and hypothalamic neuropeptide systems

Frontiers in Behavioral Neuroscience, 2016
The intake of a high fat diet (HFD), in addition to stimulating orexigenic neuropeptides in the hypothalamus while promoting overeating and reducing locomotor behavior, is known to increase inflammatory mediators that modulate neuronal systems in the ...
Kinning ePoon, Jessica Rose Barson, Hui Tin Ho, Sarah Fryer Leibowitz   +3 more
doaj   +1 more source

Containing Histories Past and Present: Making Samples in the “Huntington Collection” (1893–1921)

American Anthropologist, Volume 128, Issue 3, Page 456-468, September 2026.
ABSTRACT The Huntington Anatomical Collection (1893–1921) includes the skeletal remains of immigrants, migrants, and lifelong New York City residents. The collection's formation was coeval with the formalization of physical anthropology, and the collection was made to serve research aims centered on race and origin.
Alanna L. Warner‐Smith
wiley   +1 more source

From Past Outbreaks to Future Threats: Detecting Medical Conspiracy Theories With LLMs and Limited Labels

Expert Systems, Volume 43, Issue 9, September 2026.
ABSTRACT Online dissemination of conspiracy theories (CTs) during epidemics poses significant risks to public health. This paper addresses the problem of detecting CTs in social media posts with an emphasis on the resource‐constrained scenarios characterized by the scarcity of labelled datasets and expert annotations, and the lack of computational ...
Ipek Baris Schlicht, Damir Korenčić, Berta Chulvi, Lucie Flek, Paolo Rosso   +4 more
wiley   +1 more source

2145 Drug formulation strategies: A vital but nearly invisible component in translational education

Journal of Clinical and Translational Science, 2018
OBJECTIVES/SPECIFIC AIMS: To develop a KL2 curriculum on the science and art of drug formulation. METHODS/STUDY POPULATION: Develop training materials for KL2 scholars that outline the art of formulation development.
Robert B. MacArthur, Roger Vaughan, Barry S. Coller   +2 more
doaj   +1 more source