Results 31 to 40 of about 26,563 (215)

Effects of sugammadex and rocuronium on electro-mechanical activity of cardiac myocytes [PDF]

open access: yesKorean Journal of Anesthesiology
Background Sugammadex reverses the effects of steroidal neuromuscular-blocking agents, such as rocuronium, by encapsulating these agents. Its cardiovascular adverse effects include QTc prolongation, hypotension, bradycardia, atrioventricular block ...
Oguzhan Arun   +6 more
doaj   +1 more source

Prolonged onset and duration of action of rocuronium after accidental subcutaneous injection in a patient with chronic renal failure—a case report

open access: yesJA Clinical Reports, 2021
Background Drugs administered subcutaneously have delayed onset and prolonged duration of action versus those given intravenously. Since the duration of action of rocuronium is prolonged in patients with renal dysfunction, subcutaneous administration of ...
Akira Doshu-Kajiura   +2 more
doaj   +1 more source

Cerebral and cardiovascular effects of analgesic doses of ketamine during a target controlled general anesthesia: a prospective randomized study [PDF]

open access: yes, 2017
Introduction: Ketamine is increasingly being used in various pain settings. The purpose of this study was to assess the effect of an analgesic dose of ketamine in the bispectral index (BIS), spectral edge frequency (SEF-95), density spectral array (DSA),
Araujo, A. M.   +3 more
core   +1 more source

Life-threatening rocuronium-induced anaphylactic shock without cutaneous manifestations successfully reversed with sugammadex: a case report

open access: yesJA Clinical Reports, 2020
Background Recognition of rocuronium-induced anaphylaxis is often challenging, owing to its diverse clinical manifestations. Regarding treatment, several reports have described the efficacy of sugammadex, while conflicting reports have also been ...
Yoshiaki Takise   +7 more
doaj   +1 more source

MRGPRX2 Activation by Rocuronium: Insights from Studies with Human Skin Mast Cells and Missense Variants

open access: yesCells, 2021
Perioperative hypersensitivity (POH) to the neuromuscular blocking drug (NMBD) rocuronium was previously thought to be IgE and mast cell (MC)-mediated. However, the recent seminal observation that rocuronium induces degranulation in murine peritoneal MCs
Chalatip Chompunud Na Ayudhya   +4 more
doaj   +1 more source

Delayed-Onset Malignant Hyperthermia in Association with Rocuronium Use [PDF]

open access: yes, 2012
Purpose Two cases of malignant hyperthermia suspected to be related to the use of a nondepolarizing neuromuscular blocker are reported. Summary A pharmacogenetic disorder that may occur in as many as 1 in 3000 anesthesia procedures, malignant ...
Beggs, Ashton E.   +2 more
core   +2 more sources

The effect of magnesium sulfate concentration on the effective concentration of rocuronium, and sugammadex-mediated reversal, in isolated left phrenic nerve hemi-diaphragm preparations from the rat [PDF]

open access: yesKorean Journal of Anesthesiology, 2018
Background Perioperative magnesium sulfate (MgSO4) is used for analgesic, anti-arrhythmic, and obstetric purposes. The effects of MgSO4 on the neuromuscular blockade (NMB) induced by rocuronium, and the sugammadex reversal thereof, have not been clearly ...
Choon-kyu Cho   +6 more
doaj   +1 more source

Reduction of the rocuronium-induced withdrawal reflex by MR13A10A, a generic rocuronium with a novel solution: A randomized, controlled study.

open access: yesPLoS ONE, 2019
BackgroundRocuronium induces venous pain and the withdrawal reflex during injection. MR13A10A, generic rocuronium with a novel solution, reduced the injection-induced withdrawal reflex in rodents.
Masaru Shimizu   +5 more
doaj   +1 more source

Tracheal intubation with rocuronium using a "modified timing principle" [PDF]

open access: yesKorean Journal of Anesthesiology, 2013
BackgroundRapid sequence induction (RSI) is indicated in various situations. Succinylcholine has been the muscle relaxant of choice for RSI, and rocuronium has become an alternative medicine for patients who cannot be administered succinylcholine for ...
Min A Kwon, Jaegyok Song, Ju-Ri Kim
doaj   +1 more source

A survey of the current use of neuromuscular blocking drugs among the Middle Eastern anesthesiologists

open access: yesSaudi Journal of Anaesthesia, 2013
Background: This survey aimed to assess the extent of practice of the Middle Eastern anesthesiologists in the use of neuromuscular blocking agents (NMB) in 2012.
Abdelazeem Eldawlatly   +2 more
doaj   +1 more source

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