Simultaneous Modeling of In Vivo and In Vitro Effects of Nondepolarizing Neuromuscular Blocking Drugs [PDF]
Nondepolarizing neuromuscular blocking drugs (NDNBs) are clinically used to produce muscle relaxation during general anesthesia. This paper explores a suitable model structure to simultaneously describe in vivo and in vitro effects of three clinically used NDNBs, cisatracurium, vecuronium, and rocuronium. In particular, it is discussed how to reconcile
arxiv
Sugammadex, a neuromuscular blockade reversal agent, causes neuronal apoptosis in primary cultures. [PDF]
Sugammadex, a γ-cyclodextrin that encapsulates selectively steroidal neuromuscular blocking agents, such as rocuronium or vecuronium, has changed the face of clinical neuromuscular pharmacology.
Aguirre Rueda, Diana+10 more
core +2 more sources
Experimentally observed defect tolerance in the electronic structure of lead bromide perovskites [PDF]
Point defect tolerance in materials, which extends operational lifetime, is essential for societal sustainability, and the creation of a framework to design such properties is a grand challenge in the material sciences. Using three prototypical lead bromide perovskites in single crystal form and high-resolution synchrotron-based X-ray spectroscopy, we ...
arxiv
Exciton-relaxation dynamics in lead halides [PDF]
We survey recent comprehensive studies of exciton relaxation in the crystals of lead halides. The luminescence and electron-spin-resonance studies have revealed that excitons in lead bromide spontaneously dissociate and both electrons and holes get self-trapped individually. Similar relaxation has been also clarified in lead chloride. The electron-hole
arxiv +1 more source
Effects of rocuronium bromide on globe position and respiratory function in isoflurane-anesthetized dogs: a comparison between three different dosages. [PDF]
Objective To evaluate the effect on globe position and respiration of three dosages of intravenous rocuronium in isoflurane-anesthetized dogs. Animal studied Thirty-two dogs anesthetized for ophthalmic procedures.
BARSOTTI, GIOVANNI+4 more
core +1 more source
Background: Rapid sequence induction and intubation aims to secure the airway at the earliest possible time to protect the airway. Succinylcholine is the most popular drug for this but rocuronium is an alternative when succinyl choline is contraindicated.
Shajahan I, Ramkumar V. Venkateswaran
semanticscholar +1 more source
Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
Duchenne’s muscular dystrophy (DMD) is the most common and severe form of myopathy. Patients with DMD are more sensitive to sedative, anesthetic, and neuromuscular blocking agents which may result in intraoperative and early postoperative cardiovascular ...
Ahmed Abdelgawwad Wefki Abdelgawwad Shousha+3 more
doaj +1 more source
Ab-initio study of the effect of bromide mixing into RbPbI$_3$ on the structural, electronic and optical properties [PDF]
The ultra-high efficiency and cost-effective photovoltaics based on halide preovskites have brought a revolution to ongoing photovoltaic research, surpassing the expectations of the scientific community. However, structural stability is a severe issue that hinders their wide-scale integration at the device level.
arxiv
Autonomic Dysfunction Because of Severe Tetanus in an Unvaccinated Child [PDF]
Tetanus is rare in a country with a national vaccination program. When it does occur, the associated autonomic dysfunction is a challenge for physicians.
Chen, Li-Kuang+5 more
core +2 more sources
Safety of sugammadex for myasthaenia gravis patients undergoing general anaesthesia: a retrospective database study [PDF]
BACKGROUND: Using neuromuscular blocking drugs (NMBDs) for patients with myasthaenia gravis remains a challenge in perioperative management. Sugammadex has enabled the safe use of NMBDs.
Kawakami, Koji+4 more
core +2 more sources