Results 111 to 120 of about 6,023,542 (380)

Insights into mitotic checkpoint by integrating CRISPR and RNAi

open access: yesMolecular & Cellular Oncology, 2019
Our recent study of the mitotic checkpoint protein BUB1 (budding uninhibited by benzimidazoles 1) revealed several apparent BUB1 knock-out cell lines expressing low levels of BUB1 protein sufficient to support spindle assembly checkpoint activity.
Gang Zhang
doaj   +1 more source

Conformal invariants from nodal sets. I. Negative Eigenvalues and Curvature Prescription [PDF]

open access: yes, 2012
In this paper, we study conformal invariants that arise from nodal sets and negative eigenvalues of conformally covariant operators; more specifically, the GJMS operators, which include the Yamabe and Paneitz operators.
Andrea Malchiodi   +4 more
core  

Next-generation sequencing applied to a large French cone and cone-rod dystrophy cohort: mutation spectrum and new genotype-phenotype correlation

open access: yesOrphanet Journal of Rare Diseases, 2015
BackgroundCone and cone-rod dystrophies are clinically and genetically heterogeneous inherited retinal disorders with predominant cone impairment. They should be distinguished from the more common group of rod-cone dystrophies (retinitis pigmentosa) due ...
É. Boulanger-Scemama   +13 more
semanticscholar   +1 more source

MOFs and COFs in Electronics: Bridging the Gap between Intrinsic Properties and Measured Performance

open access: yesAdvanced Functional Materials, EarlyView.
Metal‐organic frameworks (MOFs) and covalent organic frameworks (COFs) hold promise for advanced electronics. However, discrepancies in reported electrical conductivities highlight the importance of measurement methodologies. This review explores intrinsic charge transport mechanisms and extrinsic factors influencing performance, and critically ...
Jonas F. Pöhls, R. Thomas Weitz
wiley   +1 more source

Enhanced Mutant Compensates for Defects in Rhodopsin Phosphorylation in the Presence of Endogenous Arrestin-1

open access: yesFrontiers in Molecular Neuroscience, 2018
We determined the effects of different expression levels of arrestin-1-3A mutant with enhanced binding to light-activated rhodopsin that is independent of phosphorylation.
Srimal Samaranayake   +5 more
doaj   +1 more source

Anisotropic viscoelastic phase separation in polydisperse hard rods: non-sticky gelation [PDF]

open access: green, 2018
Claudia Ferreiro-Córdova   +2 more
openalex   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

open access: yesAdvanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria   +7 more
wiley   +1 more source

Research on the continuous casting process of CuCrZr alloys with the addition of scandium dedicated for resistance welding electrodes

open access: yesMetalurgija, 2022
The article presents the results of research on the metallurgical synthesis of CuCrZr copper alloys with the addition of scandium as a new material for spot welding electrodes for the resistance spot welding of Zn-coated steel sheets. The tested material
K. Franczak   +6 more
doaj  

Cone rod dystrophies [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2007
Cone rod dystrophies (CRDs) (prevalence 1/40,000) are inherited retinal dystrophies that belong to the group of pigmentary retinopathies. CRDs are characterized by retinal pigment deposits visible on fundus examination, predominantly localized to the macular region. In contrast to typical retinitis pigmentosa (RP), also called the rod cone dystrophies (
openaire   +3 more sources

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