Results 221 to 230 of about 459,232 (311)

Hantavirus seroprevalence and associated factors for exposure in south-central Uganda. [PDF]

Emerg Microbes Infect
Katushabe G, Ssempijja V, Rao D, Nalwadda J, Rosenke K, Reynolds SJ, Omooja J, Biraro IA, Grabowski MK, Mihalakakos EA, Galiwango RM, Ssekubugu R, Byarugaba DK, Feldmann H, Hawman DW.   +14 more
europepmc   +1 more source

Animal models of idiopathic membranous nephropathy: Recent advances and future perspectives

Animal Models and Experimental Medicine, EarlyView.
This review focuses on the evolution of idiopathic membranous nephropathy (IMN) animal models from traditional approaches (Heymann nephritis, C‐BSA, APA) to antigen‐specific models (PLA2R, THSD7A), critically evaluating their advances and limitations in replicating human IMN pathology.
Qiuying Liu, Huixian Bian, Jianhua Liu, Lina Wu, Zhijie Zhang, Hongli Zhao, Xiaosong Qin   +6 more
wiley   +1 more source

Evaluation of cardiac histology and cell death markers during the progression of diabetes in a streptozotocin‐induced diabetes rat model

Animal Models and Experimental Medicine, EarlyView.
Daily insulin administration in streptozotocin‐induced diabetic rats prevented cardiac damage associated with diabetic cardiomyopathy, including hypertrophy, fibrosis, and expression of cell death markers, at 12 weeks. However, cyclophilin D, a marker of mitochondrial permeability transition pore‐opening‐associated cell death (necrosis), was observed ...
Tamara Sáez, Ivo Carrasco‐Wong, Juan Varas, Sebastián San Martín, Jaime A. Riquelme, Rienzi Díaz‐Navarro   +5 more
wiley   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen   +11 more
wiley   +1 more source

The <i>MV Hondius</i> Warning: Hantavirus Surveillance Blind Spots. [PDF]

Lancet Reg Health Eur
Guo J, Semenza JC.
europepmc   +1 more source

Animal models in molecular biology research: Challenges, ethical imperatives, and the path to human‐relevant translation

Animal Models and Experimental Medicine, EarlyView.
The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi, Md. Taslim Sarker, Ferdous‐Ul‐Haque Joy, Shahriar Mohd Shams, Tahmina Foyez, Md. Abdul Mazid, Syed Masudur Rahman Dewan   +6 more
wiley   +1 more source

<i>Streptobacillus moniliformis</i> bacteremia in an afebrile patient: A rare case report. [PDF]

IDCases
Wu Z, Zhang L, Shi L, Wang C, Cao W.
europepmc   +1 more source

Development of a sheep model of knee osteoarthritis and preliminary magnetic resonance–guided focused ultrasound evaluation

Animal Models and Experimental Medicine, EarlyView.
This study was the first to induce knee osteoarthritis (KOA) by administering monoiodoacetate to sheep to develop a novel animal model of KOA. Radiographic, gross, and histological changes consistent with KOA developed in all sheep; however, only two sheep developed behavioral signs of KOA pain. Magnetic resonance–guided focused ultrasound (MRgFUS) was
Xuejun Du, Andrew Spiteri, Arik Hananel, Abhijit Dighe, Richard J. Price, Xinlin Yang, Quanjun Cui   +6 more
wiley   +1 more source

Zoonotic cutaneous leishmaniasis caused by Leishmania major: Do humans play a role in amplifying transmission? [PDF]

Parasite
Aoun K, Maatallah F, Bouratbine A.
europepmc   +1 more source