Results 261 to 270 of about 695,363 (337)
The impact of land use change on mycorrhizal fungi and their associations with rodents: insights from a temperate forest in Mexico. [PDF]
Gil-Fernández M+7 more
europepmc +1 more source
Prevention and treatment of diabetic kidney disease (DKD) have become a major global public health challenge. This study shed new light on the underlying pathogenic mechanisms of podocyte injury in DKD and highlights the therapeutic potential of mitigating podocyte injury through inhibition of the RIPK3/NF‐κB p65‐mediated inflammatory response as a ...
Lu'an Li+10 more
wiley +1 more source
Genomic and transcriptomic insights into vertebrate host-specific <i>Lactobacillus johnsonii</i> adaptation in the gastrointestinal tract. [PDF]
Ravi K, Falkowski NR, Huffnagle GB.
europepmc +1 more source
A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria+5 more
wiley +1 more source
Resolving anxiety-like behaviour inconsistencies in the elevated plus maze by tracking exploration depth and timing. [PDF]
Zelko MD+3 more
europepmc +1 more source
This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song+15 more
wiley +1 more source
Reducing NMDA Receptor Function Impacting Learning and Electroencephalogram Oscillations. [PDF]
Dexter TD, Young JW.
europepmc +1 more source
Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing+4 more
wiley +1 more source