Results 41 to 50 of about 882,412 (385)
Translational Psychiatry, 2018 Autism spectrum disorder (ASD) is a pervasive neurodevelopmental syndrome with a high human and economic burden. The pathophysiology of ASD is largely unclear, thus hampering development of pharmacological treatments for the core symptoms of the disorder.
J. Horder +8 more
semanticscholar +1 more source
By hook or by crook? Morphometry, competition and cooperation in rodent sperm [PDF]
, 2007 Background Sperm design varies enormously across species and sperm competition is thought to be a major factor influencing this variation. However, the functional significance of many sperm traits is still poorly understood.
AH Harcourt +40 more
core +14 more sources
Attenuated palmitoylation of serotonin receptor 5-HT1A affects receptor function and contributes to depression-like behaviors [PDF]
, 2019 The serotonergic system and in particular serotonin 1A receptor (5-HT1AR) are implicated in major depressive disorder (MDD). Here we demonstrated that 5-HT1AR is palmitoylated in human and rodent brains, and identified ZDHHC21 as a major palmitoyl ...
Bazovkina, Daria +9 more
core +1 more source
Rodent models in neuroscience research: is it a rat race?
Disease Models & Mechanisms, 2016 Rodents (especially Mus musculus and Rattus norvegicus) have been the most widely used models in biomedical research for many years. A notable shift has taken place over the last two decades, with mice taking a more and more prominent role in biomedical ...
B. Ellenbroek, J. Youn
semanticscholar +1 more source
Social anhedonia as a Disrupted-in-Schizophrenia 1-dependent phenotype
Scientific Reports, 2022 Deficits in social interaction or social cognition are key phenotypes in a variety of chronic mental diseases, yet, their modeling and molecular dissection are only in their infancy.
Mohammad Seidisarouei +5 more
doaj +1 more source
RNA Virus Diversity in Birds and Small Mammals From Qinghai–Tibet Plateau of China
Frontiers in Microbiology, 2022 Most emerging and re-emerging viruses causing infectious diseases in humans and domestic animals have originated from wildlife. However, current knowledge of the spectrum of RNA viruses in the Qinghai-Tibet Plateau in China is still limited.
Wentao Zhu +18 more
doaj +1 more source
Interactions between landscape changes and host communities can regulate echinococcus multilocularis transmission [PDF]
, 2003 An area close to the Qinghai-Tibet plateau region and subject to intensive deforestation contains a large focus of human alveolar echinococcosis while sporadic human cases occur in the Doubs region of eastern France.
Bao, G +10 more
core +2 more sources
Cisplatin-Induced Rodent Model of Kidney Injury: Characteristics and Challenges
BioMed Research International, 2018 Cisplatin is an antitumor drug used in the treatment of a wide variety of malignancies. However, its primary dose-limiting side effect is kidney injury, which is a major clinical concern.
M. Perše, Ž. Večerić-Haler
semanticscholar +1 more source
Frontiers in Behavioral Neuroscience, 2021 The basal forebrain cholinergic system is involved in cognitive processes, but the role of the basal forebrain cholinergic system in depression is unknown.
Linghong Chen +13 more
doaj +1 more source
Microbiome, 2018 Rodents represent around 43% of all mammalian species, are widely distributed, and are the natural reservoirs of a diverse group of zoonotic viruses, including hantaviruses, Lassa viruses, and tick-borne encephalitis viruses.
Zhiqiang Wu +24 more
semanticscholar +1 more source