Results 41 to 50 of about 459,232 (311)

Molecular mechanisms of melatonin in mitigating compound salt stress in Sophora alopecuroides revealed by physiological and transcriptomic profiling

Plant Stress
Melatonin is a conserved multifunctional signaling molecule in plants, which regulates many developmental processes and responds to stress. Although many studies have involved melatonin in plants, it is not clear whether the application of exogenous ...
Youwei Zhang, Rui Geng, Guokang Chen, Shuai Yuan, Lei Wang, Heping Fu   +5 more
doaj   +1 more source

Alarm Calling in Plateau Pika (Ochotona curzoniae): Evidence from Field Observations and Simulated Predator and Playback Experiments

Animals, 2023
Acoustic communication plays a vital role in passing or sharing information between individuals. Identifying the biological meaning of vocal signals is crucial in understanding the survival strategies of animals.
Meina Ma, Rui Hua, Darhan Bao, Guohui Ye, Zhuangsheng Tang, Limin Hua   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Rodent- borne diseases not yet reported in Iran.

, 2018
Rodent- borne diseases not yet reported in Iran.
Ahmad Mahmoudi (3246186), Mohammad Hasan Rabiee (5121902), Boris Kryštufek (3263295), Ehsan Mostafavi (406077), Roohollah Siahsarvie (5121899)   +4 more
core   +1 more source

Ecological responses of Orientallactaga sibirica: Variations in body size and trophic niche across changing habitats

Global Ecology and Conservation
In arid ecosystems, precipitation and temperature are two key factors, with altitude further shaping habitat conditions through its regulatory effects on temperature.
Qi-qige Buren, Xin Li, Guo-kang Chen, Guo-hui Ye, Shan-shan Sun, Yong-ling Jin, Ming-ming, He-Ping Fu, Shuai Yuan   +8 more
doaj   +1 more source

Machine learning identifies straightforward early warning rules for human Puumala hantavirus outbreaks

Scientific Reports, 2023
Human Puumala virus (PUUV) infections in Germany fluctuate multi-annually, following fluctuations of the bank vole population size. We applied a transformation to the annual incidence values and established a heuristic method to develop a straightforward
Orestis Kazasidis, Jens Jacob
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Knowledge, attitudes and practices of farmers on rodent pests and their management in the lowlands of the Sierra Madre Biodiversity Corridor, Philippines

, 2005
A survey of the knowledge, attitudes and practices (KAP) of 100 rice farmers and 50 coconut farmers was conducted in the coastal lowland agro-ecosystems of the Sierra Madre Biodiversity Corridor, Luzon, Philippines to identify current rodent management ...
Singleton, Grant, Stuart, Alexander, Joshi, Ravindra, Prescott, Colin   +3 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source