Results 51 to 60 of about 336,221 (215)

Seasonal Variations in the Foraging Strategies of Plateau Pikas (Ochotona curzoniae)

Animals
This study investigates the foraging habits and dietary niche characteristics of plateau pikas (Ochotona curzoniae) by analyzing differences between the cold and warm seasons using stable isotope analysis of carbon and nitrogen in liver, muscle, and fur ...
Longming Dong, Xincheng Cai, Ruixun Gan, Jing Zhang, Rui Dong, Kechi Dong, Limin Hua, Rui Zhou   +7 more
doaj   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

CO2 drove changes in global grassland GPP over the past decade

Ecological Indicators
Global climate change has profoundly affected grassland ecosystems. However, the spatial patterns and underlying mechanisms by which environmental drivers influence global grassland gross primary productivity (GPP) remain insufficiently understood.
Zhe Meng, Yuanyuan Hao, Xuexia Liu, Limin Hua, Yujie Niu   +4 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Mound-building by plateau pikas modulates the greenhouse gas balance

Global Ecology and Conservation
The plateau pika (Ochotona curzoniae) is a burrowing mammal of the alpine meadows on the Tibetan Plateau. Its digging activity reshapes the vertical soil structure, forming heterogeneous soil mounds that significantly alter the local microenvironment ...
Yuanyuan Li, Rui Dong, Xincheng Cai, Kechi Dong, Xiaoqian Zhao, Martin Pfeiffer, Limin Hua, Yujie Niu   +7 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

High-resolution early warning system for human Puumala hantavirus infection risk in Germany

Scientific Reports
The fluctuation of human infections by the Puumala orthohantavirus (PUUV) in Germany has been linked to weather and phenology parameters that drive the population growth of its host species.
Orestis Kazasidis, Anke Geduhn, Jens Jacob   +2 more
doaj   +1 more source

Spatiotemporal Activity Patterns of Sympatric Rodents and Their Predators in a Temperate Desert-Steppe Ecosystem

Animals
Understanding how prey and predator species partition activity patterns across time and space is essential for elucidating behavioral adaptation and ecological coexistence.
Caibo Wei, Yijie Ma, Yuquan Fan, Xiaoliang Zhi, Limin Hua   +4 more
doaj   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source