Results 121 to 130 of about 9,520,639 (370)

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

Pathogenesis of FUS-associated ALS and FTD: insights from rodent models

Acta Neuropathologica Communications, 2016
Disruptions to genes linked to RNA processing and homeostasis are implicated in the pathogenesis of two pathologically related but clinically heterogeneous neurodegenerative diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
M. Nolan, K. Talbot, O. Ansorge
semanticscholar   +1 more source

Miniaturized Wireless tDCS With Concentric Electrodes for Targeted Cortical Stimulation in Freely Moving Mice

Advanced Healthcare Materials, EarlyView.
This study introduces a wireless and miniaturized concentric‐electrode tDCS (CE‐tDCS) system tailored for freely moving mice. The device enables focal and multi‐site cortical stimulation via a lightweight, Bluetooth‐controlled platform. By integrating local neuromodulation with real‐time behavioral analysis, the system provides a robust tool for ...
Minseok Kim, Sehwan Park, Haeyun Lee, Giheon Kim, Namsun Chou, Hyogeun Shin   +5 more
wiley   +1 more source

Systematic surveillance tools to reduce rodent pests in disadvantaged urban areas can empower communities and improve public health

Scientific Reports
Rodents are notorious pests, known for transmitting major public health diseases and causing agricultural and economic losses. The lack of site-specific and national standardised rodent surveillance in several disadvantaged communities has rendered ...
Adedayo Michael Awoniyi, Ana Maria Barreto, Hernan Dario Argibay, Juliet Oliveira Santana, Fabiana Almerinda G. Palma, Ana Riviere-Cinnamond, Gauthier Dobigny, Eric Bertherat, Luther Ferguson, Steven Belmain, Federico Costa   +10 more
doaj   +1 more source

Lurking in the shadows: emerging rodent infectious diseases.

ILAR journal, 2008
Rodent parvoviruses, Helicobacter spp., murine norovirus, and several other previously unknown infectious agents have emerged in laboratory rodents relatively recently.
D. Besselsen, C. Franklin, R. Livingston, L. Riley   +3 more
semanticscholar   +1 more source

Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity [PDF]

, 2017
Cisplatin-induced ototoxicity is one of the major factors limiting cisplatin chemotherapy. Ototoxicity results from damage to outer hair cells (OHCs) and other regions of the cochlea.
Bhatta, Puspanjali, Borse, Vikrant, Dhukhwa, Asmita, FH Al Aameri, Raheem, Ghosh, Sumana, Kaur, Tejbeer, Lowy, Michelle, Mukherjea, Debashree, Ramkumar, Vickram, Rybak, Leonard P, Sheehan, Kelly, Sheth, Sandeep, Tupal, Srinivasan   +12 more
core   +2 more sources

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia

Clinical Interventions in Aging, 2017
Evaluation of behavior and cognition in rodent models underpins mechanistic and interventional studies of brain aging and neurodegenerative diseases, especially dementia.
Devin Wahl, Sean C. P. Coogan, Samantha M. Solon-Biet, R. de Cabo, James B. Haran, D. Raubenheimer, V. Cogger, M. Mattson, S. Simpson, D. L. Le Couteur   +9 more
semanticscholar   +1 more source

The impact of low erythrocyte density in human blood on the fitness and energetic reserves of the African malaria vector Anopheles gambiae [PDF]

, 2013
Background Anaemia is a common health problem in the developing world. This condition is characterized by a reduction in erythrocyte density, primarily from malnutrition and/or infectious diseases such as malaria.
A Dao, A De Loof, A Rivero, AN Clements, B Schiefer, BA Okech, C Garrett-Jones, C Stone, D Proven, DE Impoinvil, E Van Handel, E Van Handel, E Van Handel, EO Lyimo, F Aboagye-Antwi, F Aboagye-Antwi, H Briegel, H Briegel, H Briegel, H Briegel, H Hurd, H Hurd, H Manda, Heather M Ferguson, HM Ferguson, II Abdelrahim, JC Beier, JC Hogg, JH Oliveira, JK Nayar, JM Mukiibi, JN Shieh, JR Carey, KA Carlson, LA Baton, Lisa C Ranford-Cartwright, M Bukar, MJ Crawley, NR Van den Broek, P Hougaard, PFL Boreham, PJ Taylor, PW Price, R Carter, R Ross, RA Anderson, RS Nasci, S Noushin Emami, SC Stearns, T Flatt, TK Nkuo-Akenji, TL Daniel, VF Fairbanks, WA Foster, WA Maier   +54 more
core   +3 more sources

Battery‐Free Dual‐Channel Wireless Neurostimulator Using Passive Circuitry for Neuropathic Pain Modulation

Advanced Healthcare Materials, EarlyView.
A compact, wireless neural stimulator featuring a novel tapping inductor enables selective and independent stimulation of the motor cortex in rats via a single receiver coil. This minimally invasive system effectively reduces neuropathic pain through targeted cortical activation, offering a new avenue for bioelectronic pain therapies and advancing ...
Jeongju Moon, Kyungmo Seong, Hyeon Gyu Kim, Wonki Mun, Seung Hyun Min, Sung‐Yun Park, Joonsoo Jeong, Chin Su Koh, Hyun Ho Jung, Kyungsik Eom   +9 more
wiley   +1 more source