Results 101 to 110 of about 2,614,376 (299)

The Bioeconomics of Controlling an African Rodent Pest Species [PDF]

The paper treats the economy of controlling an African pest rodent, the multimammate rat, causing major damage in maize production. An ecological population model is presented and used as a basis for the economic analyses carried out at the village level
Nils Chr. Stenseth, Anders Skonhoft, Loth S.A. Mulungu, Herwig Leirs, Harry P. Andreassen   +4 more
core  

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Negative attitudes of an indigenous community are associated with lethal control of rodents in a temperate forest of Mexico

Ecological Solutions and Evidence
Rodents have been unwanted human commensals for millennia, as they can decimate crops and spread diseases. However, rodents perform essential ecological functions, and promoting awareness about this could boost native rodent conservation and increase ...
Margarita Gil‐Fernández, Diana Lucrecia Ruíz‐Ramírez, Johannes J. Le Roux, Christian A. Delfín‐Alfonso, M. Cristina MacSwiney G., Alexandra J. R. Carthey, Ross T. Shackleton   +6 more
doaj   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Critical analysis of translational potential of rodent models of white matter pathology across a wide spectrum of human diseases

Cell Death and Disease
Rodents are the most commonly used laboratory animals in medical research. However, significant evolutionary divergences between humans and rodents, particularly in the complexity of white matter connectome, which are fundamentally shaped by myelin as ...
Wenxuan Zhou, Shiyue Xia, Chenmeng Wang, Qingwu Yang, Alexei Verkhratsky, Jianqin Niu   +5 more
doaj   +1 more source

Jennifer-Angoh/Pine-Marten-Rodent: v.1.0.1

<p>Code for article "How do microtine rodent abundance, snow and landscape parameters influence pine marten Martes martes population dynamics?".
Siow Yan Jennifer Angoh
core   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

CNTN2 Deficiency Disrupts Ascending Auditory Neuroglial Interactions and Redox Homeostasis in Neural Presbycusis

Advanced Science, EarlyView.
. ABSTRACT Neural presbycusis disrupts auditory timing and speech perception, yet its molecular basis remains poorly understood. This study identifies Cntn2 as the Ranvier's nodal molecule significantly downregulated in aged auditory nerves. Cntn2 heterozygous knockout (Cntn2+/−) mice showed elevated auditory brainstem response thresholds and prolonged
Penghui Chen, Jingyi Zhu, Sihan Huang, Beibei Xu, Maoli Duan, Jingrong Lv, Jiarui Chen, Jun Yang, Shule Hou   +8 more
wiley   +1 more source

Chemical-Based Rodent Control Programs as a Zoonosis Control Measure: Proposal of Guidelines for Empirical Proof Studies

Rodent-borne diseases threaten global public health, impacting the urban poor. Despite widespread application of rodenticide in rodent/rodent-borne disease control programs, empirical evidence demonstrating their effectiveness is lacking.
Caio Graco Zeppelini, Zeppelini, Caio Graco,, Swedish University of Agricultural Sciences.   +2 more
core   +1 more source

The Impacts of Climate Change on Water-, Food-, Vector- and Rodent-Borne Diseases [PDF]

, 2008
This chapter, The Impacts of Climate Change on Water-, Food-, Vector-, and Rodent-Borne Diseases, is from the book Human Health in a Changing Climate: A Canadian Assessment of Vulnerabilities and Adaptive Capacity edited by Jacinthe ...
Charron, Dominique, Fleury, Manon, Ogden, Nicholas, Schuster Wallace, Corinne, Lindsay, Robbin   +4 more
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