Results 51 to 60 of about 2,614,376 (299)

An analysis of rodent density patterns and its spatial–temporal correlations using geographically and temporally weighted regression in southeastern China

Frontiers in Veterinary Science
IntroductionRodents are significant vectors, harboring diverse pathogenic microorganisms which can spread a variety of infectious diseases. Surveillance on rodent density patterns should be prioritized as early warning indicators for prevention and ...
Mingyu Luo, Mingyu Luo, Jinna Wang, Jinna Wang, Mingyong Tao, Hanran Ji, Guoqin Jiang, Qinmei Liu, Qinmei Liu, Tianqi Li, Tianqi Li, Zhou Guan, Zhou Guan, Juan Hou, Juan Hou, Zhenyu Gong, Zhenyu Gong   +16 more
doaj   +1 more source

Are rodent models of Parkinson’s disease behaving as they should? [PDF]

Behavioural Brain Research, 2018
In recent years our understanding of Parkinson's disease has expanded both in terms of pathological hallmarks as well as relevant genetic influences. In parallel with the aetiological discoveries a multitude of PD animal models have been established. The vast majority of these are rodent models based on environmental, genetic and mechanistic insight. A
Vingill, Siv, Connor-Robson, Natalie, Wade-Martins, Richard   +2 more
openaire   +3 more sources

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

PIODERMITE PROFUNDA POR Corynebacterium pseudotuberculosis EM CUTIA (Dasyprocta sp.)

Ciência Animal Brasileira, 2010
Bacterial skin diseases represent a significant ratio ofrodents’ pathologies. However, in agoutis (Dasyprocta sp.), amiddle-sized rodent with geographic distribution from Central toSouth America, reports on isolated bacterial agents of ...
Kilder Dantas Filgueira, Moacir Franco de Oliveira, Jael Soares Batista, Francisco Marlon Carneiro Feijó, Valéria Veras de Paula   +4 more
doaj  

Mapping global risk of bat and rodent borne disease outbreaks to anticipate emerging threats

Scientific Reports
Future epidemics and/or pandemics may likely arise from zoonotic viruses with bat- and rodent-borne pathogens being among the prime candidates. To improve preparedness and prevention strategies, we predicted the global distribution of bat- and rodent ...
Soushieta Jagadesh, Claudia Cataldo, Wim Van Bortel, Esther Van Kleef, William Wint, Annapaola Rizzoli, Luca Busani, Elena Arsevska   +7 more
doaj   +1 more source

Rodent genetic models of Huntington disease

Neurobiology of Disease, 2008
Huntington disease (HD) is a dominantly inherited human neurodegenerative disorder characterized by motor deficits, cognitive impairment, and psychiatric symptoms leading to inexorable decline and death. Since the identification of the huntingtin gene and the characteristic expanded CAG repeat/polyglutamine mutation, multiple murine genetic models and ...
Mary Y. Heng, Peter J. Detloff, Roger L. Albin   +2 more
openaire   +3 more sources

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Rodent communities in a changing environment: implications for human health in the Alps - an introduction to the project [PDF]

, 2012
Complex human-related environmental changes at the global level are of a particularly high priority in ecological research. Global climate and land-use changes may alter the richness of biodiversity and related changes in distribution of parasites and ...
Hauffe, Heidi Christine, Rizzoli, Annapaola, Konecny, Adam   +2 more
core   +1 more source

Knowledge, risk perceptions and practices regarding rodents and their associated pathogens: environmental consultants in Chile

One Health Outlook
Background Rodents play essential ecological roles but are also significant reservoirs of zoonotic pathogens, posing risks to humans. Individuals with frequent occupational contact with rodents face an elevated risk of exposure to rodent-borne diseases ...
Esteban Vásquez, Rodrigo Salgado, Hugo Mendoza, Diego A. Peñaranda, Darío Moreira-Arce, André V. Rubio   +5 more
doaj   +1 more source

Animal Models of Metabolic Disorders in the Study of Neurodegenerative Diseases: An Overview

Frontiers in Neuroscience, 2021
The incidence of metabolic disorders, as well as of neurodegenerative diseases—mainly the sporadic forms of Alzheimer’s and Parkinson’s disease—are increasing worldwide.
Andreza Fabro de Bem, Rachel Krolow, Hémelin Resende Farias, Victória Linden de Rezende, Daniel Pens Gelain, José Cláudio Fonseca Moreira, João Miguel das Neves Duarte, João Miguel das Neves Duarte, Jade de Oliveira   +8 more
doaj   +1 more source