Results 21 to 30 of about 13,163,334 (326)

Effect of rodent density on tick and tick-borne pathogen populations: consequences for infectious disease risk

Parasites & Vectors, 2020
Background Rodents are considered to contribute strongly to the risk of tick-borne diseases by feeding Ixodes ricinus larvae and by acting as amplifying hosts for pathogens. Here, we tested to what extent these two processes depend on rodent density, and
Aleksandra I. Krawczyk, Gilian L. A. van Duijvendijk, Arno Swart, Dieter Heylen, Ryanne I. Jaarsma, Frans H. H. Jacobs, Manoj Fonville, Hein Sprong, Willem Takken   +8 more
doaj   +2 more sources

Animal Models of Metabolic Disorders in the Study of Neurodegenerative Diseases: An Overview

Frontiers in Neuroscience, 2021
The incidence of metabolic disorders, as well as of neurodegenerative diseases—mainly the sporadic forms of Alzheimer’s and Parkinson’s disease—are increasing worldwide.
Andreza Fabro de Bem, Rachel Krolow, Hémelin Resende Farias, Victória Linden de Rezende, Daniel Pens Gelain, José Cláudio Fonseca Moreira, João Miguel das Neves Duarte, João Miguel das Neves Duarte, Jade de Oliveira   +8 more
doaj   +2 more sources

Methods for Rodent Control to Prevent Zoonotic Diseases: A Systematic Review of Studies from Africa

Zoonotic Diseases
Background: Africa is a continent with diverse climates, landscapes, rainfall patterns, and vegetation types, all of which significantly influence its mammalian fauna, particularly small mammals.
Mwajabu Selemani, Abdul S. Katakweba, Shabani Kiyabo Motto, Rhodes H. Makundi   +3 more
doaj   +3 more sources

Rodent reservoirs of future zoonotic diseases [PDF]

Proceedings of the National Academy of Sciences, 2015
Significance Forecasting reservoirs of zoonotic disease is a pressing public health priority. We apply machine learning to datasets describing the biological, ecological, and life history traits of rodents, which collectively carry a disproportionate number of zoonotic pathogens.
Barbara A. Han, J. Schmidt, Sarah Bowden, J. Drake   +3 more
semanticscholar   +4 more sources

Validation of Reference Genes via qRT-PCR in Multiple Conditions in Brandt’s Voles, Lasiopodomys brandtii

Animals, 2021
The choice of optimal reference gene is challenging owing to the varied expression of reference genes in different organs, development stages, and experimental treatments. Brandt’s vole (Lasiopodomys brandtii) is an ideal animal to explore the regulatory
Lin Tian, Yan Chen, Da-Wei Wang, Xiao-Hui Liu   +3 more
doaj   +1 more source

Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases

Nature Communications, 2023
Microglial activation plays central roles in neuroinflammatory and neurodegenerative diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein (TSPO) is widely used for localising inflammation in vivo, but its quantitative ...
E. Nutma, N. Fancy, M. Weinert, S. Tsartsalis, M. Marzin, R. Muirhead, Irene Falk, M. Breur, J. de Bruin, David Hollaus, Robin Pieterman, J. Anink, D. Story, S. Chandran, Jiabin Tang, M. C. Trolese, T. Saito, T. Saido, Katharine H. Wiltshire, Paula Beltran-Lobo, Alexandra E. M. Phillips, Jack P. Antel, Luke M. Healy, Marie-France Dorion, D. Galloway, Rochelle Y. Benoit, Quentin Amossé, Kelly Ceyzériat, Aurélien M. Badina, E. Kövari, C. Bendotti, E. Aronica, Carola I. Radulescu, J. Wong, A. Barron, Amy M. Smith, Samuel J. Barnes, David W. Hampton, P. Van Der Valk, S. Jacobson, O. Howell, D. Baker, M. Kipp, Hannes Kaddatz, B. Tournier, P. Millet, P. Matthews, C. Moore, S. Amor, David R. Owen   +49 more
semanticscholar   +1 more source

No Evidence for the Presence of SARS-CoV-2 in Bank Voles and Other Rodents in Germany, 2020–2022

Pathogens, 2022
Rodentia is the most speciose mammalian order, found across the globe, with some species occurring in close proximity to humans. Furthermore, rodents are known hosts for a variety of zoonotic pathogens. Among other animal species, rodents came into focus
Kerstin Wernike, Stephan Drewes, Calvin Mehl, Christin Hesse, Christian Imholt, Jens Jacob, Rainer G. Ulrich, Martin Beer   +7 more
doaj   +1 more source

Behavioral tests for evaluating the characteristics of brain diseases in rodent models: Optimal choices for improved outcomes (Review).

Molecular Medicine Reports, 2022
Behavioral assessment is the dominant approach for evaluating whether animal models of brain diseases can successfully mimic the clinical characteristics of diseases.
Lingyi Huang, Dongqiong Xiao, Hao Sun, Yi Qu, Xiao-Juan Su   +4 more
semanticscholar   +1 more source

Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases

bioRxiv, 2022
Microglial activation plays central roles in neuro-inflammatory and neurodegenerative diseases. Positron emission tomography (PET) targeting 18kDa Translocator Protein (TSPO) is widely used for localising inflammation in vivo, but its quantitative ...
E. Nutma, N. Fancy, M. Weinert, M. Marzin, S. Tsartsalis, R. Muirhead, Irene Falk, J. de Bruin, David Hollaus, Robin Pieterman, J. Anink, D. Story, S. Chandran, Jiabin Tang, M. C. Trolese, T. Saito, T. Saido, Katie M. Wiltshire, Paula Beltran-Lobo, Alexandra Philips, J. Antel, Luke M. Healy, C. Moore, C. Bendotti, E. Aronica, Carola I. Radulescu, Samuel J. Barnes, David W. Hampton, P. Van Der Valk, S. Jacobson, P. Matthews, S. Amor, David R. Owen   +32 more
semanticscholar   +1 more source

Land-use change and rodent-borne diseases: hazards on the shared socioeconomic pathways

Philosophical Transactions of the Royal Society of London. Biological Sciences, 2021
Land-use change has a direct impact on species survival and reproduction, altering their spatio-temporal distributions. It acts as a selective force that favours the abundance and diversity of reservoir hosts and affects host–pathogen dynamics and ...
Gabriel E. García-Peña, André V. Rubio, Hugo Mendoza, Miguel Fernandez, Matthew T. Milholland, A. A. Aguirre, G. Suzán, C. Zambrana-Torrelio   +7 more
semanticscholar   +1 more source