Results 141 to 150 of about 203,814 (292)

Toxin-Based Rodent Models of Parkinson’s Disease

, 2020
M. Angela Cenci, Véronique Sgambato
openalex   +2 more sources

P3–289: Histamine H3 antagonists in Alzheimer's disease: Exploring the translational disconnect between rodent models and humans [PDF]

, 2013
Hugo Geerts, Äthan Spiros, Patrick J. Roberts   +2 more
openalex   +1 more source

Prefrontal Cortex Development in Health and Disease: Lessons from Rodents and Humans [PDF]

, 2020
Mattia Chini, Ileana L. Hanganu‐Opatz
openalex   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Influence of human intervention on rodent population dynamics in Southwest China. [PDF]

One Health
Zhao W, Li Y, Lin D, Lu J, Lou Z, Li X, Liu Z, Li S, Wang J, Cao R, Gao Z, Shao Z, Li R.   +12 more
europepmc   +1 more source

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease

, 2014
Jennifer C. Arnold, Michael F. Salvatore
openalex   +2 more sources

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

Advanced Science, EarlyView.
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu, Zehua Zhang, Kai Zheng, Ziqi Zhu, Yong Zhu, Abdukahar Kiram, Lei Zhao, Huihui Chen, Zhu Xu, Xihua Li, Beicheng Sun, Zhijian Li, Dengqiu Xu   +12 more
wiley   +1 more source

Burden of rodent-borne viruses in rodents and zoonotic risk in humans in Cambodia. [PDF]

Microbiol Spectr
Guillebaud J, Nouhin J, Hul V, Hoem T, Yanneth O, Sim M, Khun L, Y P, Heng L, Ken S, Pum L, Lim R, Meng C, Chhel K, Nuon S, Hoem S, Nguon K, Chan M, Ly S, Karlsson EA, Reynes J-M, Sakunthabhai A, Dussart P, Duong V.   +23 more
europepmc   +1 more source

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for <em>In Vivo</em> Phenotyping and Drug Monitoring [PDF]

, 2015
María V. Irazabal, Prasanna K. Mishra, Vicente E. Torres, Slobodan Macura   +3 more
openalex   +1 more source