Results 81 to 90 of about 2,409,751 (295)

Inherited Prion Diseases and Transmission to Rodents

open access: yesBrain Pathology, 1995
Clinico‐pathological phenotypes of patients with prion diseases were compared with their PrP genotyes and transmission rate to mice. Sporadic and iatrogenic CJD patients without mutation and familial CJD patients with E200K showed uniform clinico‐pathological features, synaptic‐type deposition of PrPCJD and high rate of transmission of the disease to ...
J, Tateishi, T, Kitamoto
openaire   +2 more sources

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez   +8 more
wiley   +1 more source

Community-led intensive trapping reduces abundance of key plague reservoir and flea vector

open access: yesTropical Medicine and Health
Background Zoonotic pathogens transmitted by rodents are highly prevalent in low-middle income countries and effective control measures that are easily implemented are urgently needed.
Marcela P. A. Espinaze   +10 more
doaj   +1 more source

A single rapamycin dose protects against late-stage experimental cerebral malaria via modulation of host immunity, endothelial activation and parasite sequestration

open access: yesMalaria Journal, 2017
Background Maladaptive immune responses during cerebral malaria (CM) result in high mortality despite opportune anti-malarial chemotherapy. Rapamycin, an FDA-approved immunomodulator, protects against experimental cerebral malaria (ECM) in mice through ...
Pedro Mejia   +6 more
doaj   +1 more source

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu   +13 more
wiley   +1 more source

Methods for Rodent Control to Prevent Zoonotic Diseases: A Systematic Review of Studies from Africa

open access: yesZoonotic Diseases
Background: Africa is a continent with diverse climates, landscapes, rainfall patterns, and vegetation types, all of which significantly influence its mammalian fauna, particularly small mammals.
Mwajabu Selemani   +3 more
doaj   +1 more source

catherinesheard/rodent-tail-morphology: Data and code

open access: yes, 2023
<p>data and code for Sheard et al., The evolution of rodent tail morphology, AmNat</p ...
Catherine Sheard
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Rodent species composition in urban and forested areas in eastern Germany [PDF]

open access: yesBiodiversity Data Journal
Zoonoses are major concerns for public health and after the recent pandemic, have been under a global spotlight for their often unpredictable spread and rapid evolution.
Jasmin Firozpoor   +3 more
doaj   +3 more sources

Effectiveness of Ficus benjamina “Vaditi” and Artocarpus treculianus Elm. “Tipuho” Sap Extracts as Non-Chemical Rodent Trap

open access: yesJPAIR, 2020
Pests are organisms that can cause economic damage or become threats to the health of humans and domestic animals. Rodents are pests and are considered to be essential reservoirs of numerous diseases that infect humans, domestic animals, and other ...
William Jo Se Billote   +6 more
doaj   +1 more source

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