Results 221 to 230 of about 209,874 (261)

Lost and found in translation: the value of the human imiquimod model

British Journal of Clinical Pharmacology, EarlyView.
Topical imiquimod (IMQ), a Toll‐like receptor (TLR) 7 agonist, induces transient cutaneous inflammation and is widely used in preclinical research as a ‘psoriasis‐like’ mouse model. However, accumulating evidence indicates substantial divergence between IMQ‐driven biology and human plaque psoriasis pathogenesis.
Anouk C. Meijs, Juliette A. van den Noort, Salma Assil, Naomi B. Klarenbeek, Matthijs Moerland, Tessa Niemeyer‐van der Kolk, Robert Rissmann   +6 more
wiley   +1 more source

Andes hantavirus - A primer. [PDF]

Npj Viruses
Halwe NJ, Tscherne A, Krammer F.
europepmc   +1 more source

Preclinical animal models for onchocerciasis and loiasis: A systematic review of applications in drug screening. [PDF]

PLoS Negl Trop Dis
Ayiseh RB, Gemuh BS, Mbah GE, Ghogomu SM, Cho-Ngwa F.   +4 more
europepmc   +1 more source

Neural network modeling of Lassa fever spread and disability effects. [PDF]

Sci Rep
Sabir Z, Abdelkawy MA, Jakubec M, Ibrahim NY, Ahmed AM, Bayram M, Çiçek H.   +6 more
europepmc   +1 more source

Hanta on the Hondius - public health and bioethical perspectives of the recent <i>Andes</i> hantavirus cruise ship outbreak. [PDF]

New Microbes New Infect
Tsiodras S, Gkrania-Klotsas E, Mora-Rillo M, Gupta N, Drexler JF, Jokelainen P, Pellejero-Sagastizabal G, Barac A, Paño-Pardo JR, Lescure FX, Grobusch MP.   +10 more
europepmc   +1 more source

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Rodent models of genetic disease

Current Opinion in Genetics & Development, 2003
The genetic study of rats and mice using natural variants, natural mutations, chemical or radiation induced mutations, engineered mutations and conditional engineered mutations has provided the tools for investigating the genetics of disease. The completion of the mouse genomic sequence and progress towards sequencing the rat genome in the past year ...
Roger D, Cox, Steve D M, Brown
openaire   +2 more sources