Results 21 to 30 of about 10,821,016 (340)
Modeling Parkinson’s Disease: Not Only Rodents? [PDF]
Frontiers in Aging Neuroscience, 2021 Parkinson’s disease (PD) is a common chronic progressive multifactorial neurodegenerative disease. In most cases, PD develops as a sporadic idiopathic disease. However, in 10%–15% of all patients, Mendelian inheritance of the disease is observed in an autosomal dominant or autosomal recessive manner.
Maria Shadrina, Petr Slominsky
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Land-use change and rodent-borne diseases: hazards on the shared socioeconomic pathways
Philosophical Transactions of the Royal Society of London. Biological Sciences, 2021 Land-use change has a direct impact on species survival and reproduction, altering their spatio-temporal distributions. It acts as a selective force that favours the abundance and diversity of reservoir hosts and affects host–pathogen dynamics and ...
GE García-Peña +10 more
semanticscholar +1 more source
The microbiome and rodent models of immune mediated diseases
Mammalian Genome, 2021 Over the last six decades production of laboratory rodents have been refined with the aim of eliminating all pathogens, which could influence research results. This has, however, also created rodents with little diversity in their microbiota.
A. K. Hansen, C. H. Hansen
semanticscholar +1 more source
Modeling Parkinson’s disease in LRRK2 rodents
Neuronal Signaling, 2023 Abstract Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are associated with familial and sporadic forms of Parkinson’s disease (PD). Sporadic PD and LRRK2 PD share main clinical and neuropathological features, namely hypokinesia, degeneration of nigro-striatal dopamine neurons and α-synuclein aggregates in the form of Lewy ...
Domenicale, Chiara +2 more
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Scientific Reports, 2021 Zoonotic diseases, caused by pathogens transmitted between other vertebrate animals and humans, pose a major risk to human health. Rodents are important reservoir hosts for many zoonotic pathogens, and rodent population dynamics affect the infection ...
Mahdi Aminikhah +7 more
doaj +1 more source
Bacterial and viral rodent-borne infections on poultry farms. An attempt at a systematic review
Journal of Veterinary Research, 2023 Rodents are quite common at livestock production sites. Their adaptability, high reproductive capacity and omnivorousness make them apt to become a source of disease transmission to humans and animals.
Domanska-Blicharz Katarzyna +3 more
doaj +1 more source
Scientific Reports, 2022 Rodents living alongside humans increases the probability of encounter and also the transmission of rodent-borne diseases. Singapore’s cosmopolitan urban landscape provides a perfect setting to study the prevalence of four rodent-borne pathogens: Seoul ...
Jane Griffiths +8 more
doaj +1 more source
Consequences of nano and microplastic exposure in rodent models: the known and unknown
Particle and Fibre Toxicology, 2022 The ubiquitous nature of micro- (MP) and nanoplastics (NP) is a growing environmental concern. However, their potential impact on human health remains unknown.
W. A. da Silva Brito +5 more
semanticscholar +1 more source
Journal of Small Animal Practice, 1980 ABSTRACTThe main pet rodent species are introduced with some brief notes on their suitability as pets and normal behaviour. The general clinical features of disease are discussed with some emphasis on species variation. The important diseases that occur in the United Kingdom are described under the headings of respiratory disease, diseases of the ...
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Risk factors for human acute leptospirosis in northern Tanzania [PDF]
, 2018 Introduction: Leptospirosis is a major cause of febrile illness in Africa but little is known about risk factors for human infection. We conducted a cross-sectional study to investigate risk factors for acute leptospirosis and Leptospira ...
Allan, Kathryn J. +16 more
core +2 more sources