Results 361 to 370 of about 9,442,226 (387)

Promising rodent models in Parkinson's disease

Parkinsonism & Related Disorders, 2018
In the past decade, the study of the pathogenic mechanisms underlying neurodegeneration in Parkinson's disease (PD) has revealed a genetic component, often associated with a number of environmental risk factors. Animal models have improved our understanding of disease pathogenesis, providing significant insights into the understanding of novel ...
Imbriani P., Sciamanna G., Santoro M., Schirinzi T., Pisani A.   +4 more
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Thyroid Diseases in Rodent Species

Veterinary Clinics of North America: Exotic Animal Practice, 2014
There are an abundance of studies of thyroid disease in rodents in a laboratory setting; however, research is limited in pet rodent populations. Validated reference intervals for thyroid testing are scarce, making interpretation of blood work difficult. Hyperthyroidism and hypothyroidism have been reported in multiple rodent species, with the most data
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Fungal diseases of laboratory rodents

Veterinary Clinics of North America: Exotic Animal Practice, 2003
Although fungal disease is uncommon in rodents, dermatophytosis is the most common mycosis seen in clinical practice. T. mentagrophytes is the most common etiologic agent, and the guinea pig is the most common species affected, although there are reports in all pet and laboratory rodent species except the gerbil.
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Rodent Oncology

Veterinary Clinics of North America: Exotic Animal Practice, 2017
Cancer incidence in rodent species varies dramatically from a common occurrence in mice and rats to just a limited number of documented cases in chinchillas and degus. This article summarizes common tumors, both benign and malignant, that have been reported to occur in rodents.
Samuel E. Hocker, Raelene M. Wouda, David Eshar   +2 more
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Infectious respiratory disease in rodents [PDF]

In Practice, 2004
MOST of the current knowledge regarding respiratory disease in rodents is based on the management of laboratory rodents. The emphasis is on diagnosis, elimination and prevention of subclinical respiratory disease rather than treatment. In the author's experience, rats are the most frequently presented small mammals with respiratory problems, followed ...
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Neurological Diseases of Rabbits and Rodents

Journal of Exotic Pet Medicine, 2015
Clinical signs of neurological disease, such as head tilt, hind limb paresis or paralysis, seizures, and muscle weakness, are commonly encountered in pet rabbits, and in the authors׳ experience, less often in rodent species. Moreover, localisation of neurological lesions and establishment of a definitive diagnosis can be challenging for any of the ...
Jenna Richardson, Anna Meredith
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Inducible rodent models of acquired podocyte diseases.

AJP - Renal Physiology, 2009
Glomerular diseases remain the leading cause of chronic and end-stage kidney disease. Significant advances in our understanding of human glomerular diseases have been enabled by the development and better characterization of animal models.
J. Pippin, P. Brinkkoetter, Fionnualla C Cormack-Aboud, R. Durvasula, Peter V. Hauser, J. Kowalewska, Ronald D. Krofft, C. Logar, C. B. Marshall, Takamoto Ohse, S. Shankland   +10 more
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Thyroid Disease in Rabbits and Rodents

Veterinary Clinics of North America: Exotic Animal Practice
While thyroid disease is generally uncommon in rabbits and rodents, it is most frequently diagnosed in guinea pigs. Particularly, hyperthyroidism and thyroid neoplasms are diagnosed regularly in this species, while thyroid neoplasia is the most common thyroid disorder found in other rodents.
Milena, Thöle, Tina, Brezina
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Overview on Rodent Models of Alzheimer's Disease

Current Protocols in Neuroscience, 2005
AbstractIn Alzheimer's disease (AD), characteristic lesions develop in brain regions that subserve cognitive functions, ultimately leading to dementia. There are now several lesioned or transgenic small‐animal models of the disease that model select aspects of cognitive deficits and/or recapitulate many, but not all, of the characteristic pathologic ...
Jean-Cosme Dodart, Patrick C. May
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Parkinson’s disease: a rethink of rodent models

Experimental Brain Research, 2006
Parkinson's disease (PD) is a multifactorial disease with a complex etiology that results from genetic risk factors, environmental exposures and most likely a combination of both. Rodent models of parkinsonism aim to reproduce key pathogenic features of the syndrome including movement disorder induced by the progressive loss of dopaminergic neurons in ...
Sarah Lincoln, Glenn M. Tyndall, Matthew J. Farrer, Heather L. Melrose   +3 more
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