Results 221 to 230 of about 2,614,376 (299)

Development of a Novel Quantitative PCR Assay for Detecting <i>Schistosoma japonicum</i> in Field-Captured Rodents. [PDF]

Pathogens
Lv C, Jia J, Xu X, Li S, Sun Q, Xu J, Lin L, Liu Q, Hong Y.   +8 more
europepmc   +1 more source

Early‐Life Polyethylene Microplastic Exposure Exacerbates ADHD‐Like Behaviors in Mice via PI3K/AKT1/Nrf2 Signaling: Evidence From the Pilot Cohort and Multi‐Omics Analyses

Advanced Science, EarlyView.
Circulating polyethylene microplastic burden is positively associated with heightened ADHD symptom severity and systemic redox‐inflammatory imbalance in children. Mechanistic investigation in a developmental co‐exposure mouse model further demonstrates that microplastics aggravate ADHD‐like behaviors, dopaminergic dysregulation, and oxidative ...
Yufan Luo, Ruijin Xie, Hua Xu, Xue Xiao, Wei Xiao, Qiyang Pan, Shengjie Xu, Li Liu, Zeliang Xiao, Yue Zhou, Chenyu Sun, Yu Wu, Yueying Liu   +12 more
wiley   +1 more source

Increasing spatial scale of analysis weakens and can mask the dilution effect for hantaviruses. [PDF]

PLOS Glob Public Health
Vigueras-Galván AL, Arnathau C, Rico-Chávez O, Milholland MT, Vargas ML, Suzán G, Zambrana-Torrelio C, Castro-Arellano I, Mills JN, Morales ME, Villanueva HZ, Roche B, Arnal A.   +12 more
europepmc   +1 more source

Spray‐Dried mRNA‐LNP Powder Enabling Multi‐Route Delivery With 3‐Year Refrigerated Stability

Advanced Science, EarlyView.
Spray‐dried mRNA‐LNP powder with trehalose matrix enables reconstitution for parenteral delivery or direct administration via pulmonary and sublingual routes, maintaining protein expression comparable to liquid controls. The thermostable powder preserves colloidal stability, mRNA integrity, and biological activity for over 3 years at 2°C–8°C, while ...
Ashish Sarode, Priyal Patel, Frank DeRosa, Shrirang Karve, Regis Gervier   +4 more
wiley   +1 more source

Beyond the cruise ship: Andes hantavirus and the neglected one health dimensions of global outbreak preparedness. [PDF]

Lancet Reg Health Am
Iwu CD, Pettan-Brewer C, Iwu-Jaja C, Rabinowitz P, Meisner J.   +4 more
europepmc   +1 more source

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

<i>Calodium hepaticum</i> (syn. <i>Capillaria hepatica</i>) infection in synanthropic small mammals (rodents and shrews) in Northeastern India: Zoonotic and One Health implications. [PDF]

One Health
Milton AAP, Momin AG, Saminathan M, Srinivas K, Firake DM, Gandhale PN, Karabasanavar N, Chetri PB, Palavesam A, Ghatak S, Das S.   +10 more
europepmc   +1 more source

Baihe Zhimu Decoction ameliorates anxious depression via PI3K/AKT/mTOR pathway‐mediated neuroprotection and inhibition of hippocampal neuronal apoptosis

Animal Models and Experimental Medicine, EarlyView.
Baihe Zhimu Decoction alleviates anxious depression‐like behaviors and protects hippocampal neurons. Chemical profiling and network pharmacology reveal multiple active components acting via the PI3K/AKT/mTOR pathway, enhancing neuronal survival and function, as confirmed by multi‐level in vitro and in vivo validation.
Yuanshan Han, Kexin He, Haolan Yang, Jiacheng Dai, Ronglin Chen, Yang Liu, Yuhong Wang, Lin Tang, Hongqing Zhao   +8 more
wiley   +1 more source

Can Hantavirus cruise into the next pandemic? [PDF]

Mem Inst Oswaldo Cruz
Peng NY, Rojas-Fernandez A, Deerain JM, Aguado J, Nunes MR, Amarilla AA.   +5 more
europepmc   +1 more source

A self‐retaining mouth prop for intraoral access during periodontal surgery in rat models: A technical note

Animal Models and Experimental Medicine, EarlyView.
A mouth prop designed to mimic the oral cavity of rats was made that provided stable, self‐retaining retraction, thereby facilitating oral surgery on rodents. Compared to conventional methods, it decreased surgical time, operator fatigue, and slippage. Its use led to higher efficiency and fewer complications and it was cost effective to produce.
Saravanan Sampoornam Pape Reddy, Delfin Lovelina Francis, Vivek Kumar Thakur, Balaji Manohar, Shaili Pradhan, Shesh Rai   +5 more
wiley   +1 more source