Results 91 to 100 of about 2,405,598 (288)

Rodent species composition in urban and forested areas in eastern Germany [PDF]

open access: yesBiodiversity Data Journal
Zoonoses are major concerns for public health and after the recent pandemic, have been under a global spotlight for their often unpredictable spread and rapid evolution.
Jasmin Firozpoor   +3 more
doaj   +3 more sources

Effectiveness of Ficus benjamina “Vaditi” and Artocarpus treculianus Elm. “Tipuho” Sap Extracts as Non-Chemical Rodent Trap

open access: yesJPAIR, 2020
Pests are organisms that can cause economic damage or become threats to the health of humans and domestic animals. Rodents are pests and are considered to be essential reservoirs of numerous diseases that infect humans, domestic animals, and other ...
William Jo Se Billote   +6 more
doaj   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

open access: yesAdvanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu   +8 more
wiley   +1 more source

Systematic surveillance tools to reduce rodent pests in disadvantaged urban areas can empower communities and improve public health

open access: yesScientific Reports
Rodents are notorious pests, known for transmitting major public health diseases and causing agricultural and economic losses. The lack of site-specific and national standardised rodent surveillance in several disadvantaged communities has rendered ...
Adedayo Michael Awoniyi   +10 more
doaj   +1 more source

Use of rodents as models of human diseases

open access: yesJournal of Pharmacy And Bioallied Sciences, 2014
Advances in molecular biology have significantly increased the understanding of the biology of different diseases. However, these discoveries have not yet been fully translated into improved treatments for patients with diseases such as cancers. One of the factors limiting the translation of knowledge from preclinical studies to the clinic has been the
openaire   +3 more sources

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu   +13 more
wiley   +1 more source

The Hidden Threat: Rodent-Borne Viruses and Their Impact on Public Health

open access: yesViruses
Rodents represent the most diverse order of mammals, comprising over 2200 species and nearly 42% of global mammalian biodiversity. They are major reservoirs of zoonotic pathogens, including viruses, bacteria, protozoa, and fungi, and are particularly ...
Awad A. Shehata   +5 more
doaj   +1 more source

Effect of rodent density on tick and tick-borne pathogen populations: consequences for infectious disease risk

open access: yesParasites & Vectors, 2020
Background Rodents are considered to contribute strongly to the risk of tick-borne diseases by feeding Ixodes ricinus larvae and by acting as amplifying hosts for pathogens. Here, we tested to what extent these two processes depend on rodent density, and
Aleksandra I. Krawczyk   +8 more
doaj   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

Negative attitudes of an indigenous community are associated with lethal control of rodents in a temperate forest of Mexico

open access: yesEcological Solutions and Evidence
Rodents have been unwanted human commensals for millennia, as they can decimate crops and spread diseases. However, rodents perform essential ecological functions, and promoting awareness about this could boost native rodent conservation and increase ...
Margarita Gil‐Fernández   +6 more
doaj   +1 more source

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