Results 151 to 160 of about 2,409,751 (295)

Recapitulating In Vivo Pharmacokinetics and Size‐Dependent Nanomedicine Delivery in a Microfluidic Platform

Advanced Science, EarlyView.
A microfluidic tumor platform integrates pharmacokinetic flow control, vascular‐like barriers, and 3D tumor spheroids to emulate in vivo drug exposure. The system reproduces dynamic concentration–time profiles and enables size‐dependent nanoparticle transport and efficacy evaluation, providing a predictive framework for assessing nanomedicine ...
Su Jeong Kang, Moon Sup Yoon, Jae Min Lee, Min Jeong Jo, Chae Eun Jin, Dae Hwan Shin   +5 more
wiley   +1 more source

Differential Effect of Ivermectin on Intestinal Helminths in Multimmate Mouse (Mastomys natalensis). [PDF]

Vet Med Sci
Thomas C, Msoffe V, Mwamengele G, Kessy S, Hape E, Katusi G, Sabuni C, Makundi I, Leirs H, Machang'u R.   +9 more
europepmc   +1 more source

Rodent Model of Disease [PDF]

, 2020
openaire   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Revisiting Animal Reservoirs of Hantavirus and Other Zoonotic Viruses Associated with Cruise Travel: Impact and Prevention. [PDF]

Animals (Basel)
Bonilla-Aldana DK, Bonilla-Aldana JL, Sanchez-Rojas IC, Zambrano LI, Rodríguez-Morales AJ.   +4 more
europepmc   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Integrated Analysis of Human Hemorrhagic Fever with Renal Syndrome Cases and Rodent Hantavirus Surveillance in Zhejiang Province, China, 2025. [PDF]

Viruses
Zhang R, Zheng QH, Zhou H, Xu F, Sun YS, Sun JM, Fang LQ, Wang LP.   +7 more
europepmc   +1 more source

Ecologically-Based Management of Rodent Pests [PDF]

Farm Management,
Zhang, Zhi-Bin, Anonymous, Hinds, Lyn A., Leirs, Herwig   +3 more
core  

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Climate change, rodent ecology, and the rising risk of hantavirus outbreaks: an alarming public health concern. [PDF]

Front Microbiol
Shrivastava SR, Bobhate PS, Mendhe H, Bankar N, Tidake A, Petkar P.   +5 more
europepmc   +1 more source