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Rodent-borne and rodent-related diseases in Iran [PDF]

open access: yesComparative Clinical Pathology, 2018
Rodents cause large financial losses all over the world; in addition, these animals can also act as a reservoir and intermediate host or vector of diseases. Rodents have an important role in the distribution of diseases in an area.
Rouhullah Dehghani   +2 more
exaly   +3 more sources
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Rodent models for human diseases

European Journal of Pharmacology, 2015
One of the factors limiting the translation of knowledge from preclinical studies to the clinic has been the limitations of in vivo diseases models. Except in the case of highly controlled and regulated clinical trials, geneticists and scientists do not use humans for their experimental investigations because of the obvious risk to life.
Thierry Vandamme
exaly   +4 more sources

Transmission ecology of rodent-borne diseases: New frontiers

open access: yesIntegrative Zoology, 2015
Rodents are recognized reservoir hosts for many human zoonotic pathogens. The current trends resulting from anthropocene defaunation suggest that in the future they, along with other small mammals, are likely to become the dominant mammals in almost all ...
Kim R Blasdell   +2 more
exaly   +2 more sources

Rodent models for Alzheimer disease

Nature Reviews Neuroscience, 2018
Animal models are indispensable tools for Alzheimer disease (AD) research. Over the course of more than two decades, an increasing number of complementary rodent models has been generated. These models have facilitated testing hypotheses about the aetiology and progression of AD, dissecting the associated pathomechanisms and validating therapeutic ...
Jürgen Götz   +2 more
exaly   +6 more sources

Rodent models of genetic disease

Current Opinion in Genetics & Development, 2003
The genetic study of rats and mice using natural variants, natural mutations, chemical or radiation induced mutations, engineered mutations and conditional engineered mutations has provided the tools for investigating the genetics of disease. The completion of the mouse genomic sequence and progress towards sequencing the rat genome in the past year ...
Roger D, Cox, Steve D M, Brown
openaire   +2 more sources

Rodent and Non-Rodent Animal Models for CardioVascular Diseases

2022
Cardiovascular diseases (CVD) come under non-communicable disease (NCD) that are responsible for the leading cause of death, globally. They involve a range of pathologies viz. coronary artery disease, cerebro-vascular disease, venous thrombo-embolism, peripheral vascular disease, myocardial infarction, cardiac arrhythmias and stroke.
Irfan Ahmad Mir   +4 more
openaire   +1 more source

Endocrine Diseases of Rodents

Veterinary Clinics of North America: Exotic Animal Practice, 2008
The frequency of documented endocrine diseases in rodents and other small mammals varies considerably among the species maintained as pets, biomedical research animals, or display animals in zoos. The clinical diagnosis of endocrine diseases almost never occurs in free-ranging animals in their native habitat.
openaire   +2 more sources

Dental Disease in Rodents

Journal of Veterinary Dentistry, 1990
The dental diseases of rodents are unique because of their dental anatomy and physiology. Common problems of rodent dentitions are covered in this article including periodontal disease, stomatitis, caries, and malocclusions. The anatomy of rodent dentitions is reviewed. Treatment for these diseases is included.
Robert B. Wiggs, Heidi B. Lobprise
openaire   +1 more source

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