Results 241 to 250 of about 2,659,769 (337)

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

Impact of prenatal and postnatal nutrition on pain modulation and stress response in offspring. [PDF]

Front Nutr
Cernigliaro F, Raieli V, Correnti E, Santangelo G, Nardello R.   +4 more
europepmc   +1 more source

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans.

Journal of Clinical Investigation, 2009
E. Anderson, Mary E. Lustig, K. Boyle, Tracey L. Woodlief, D. Kane, Chien‐Te Lin, J. W. Price, Li Kang, P. Rabinovitch, H. Szeto, J. Houmard, R. Cortright, D. Wasserman, P. Neufer   +13 more
semanticscholar   +1 more source

A Serum‐Stable Antimicrobial Peptide‐Based Delivery Platform for Selective Treatment of Nontargetable and Chemoresistant Tumors

Advanced Science, EarlyView.
A modular antimicrobial‐peptide‐based therapeutic system integrating membrane‐targeted selectivity, a conformation‐driven polyethylene glycolylated blocker, and serum‐stabilizing N‐cap is developed. The optimized conjugate 270 shows potent, rapid killing of the desired tumor cells, high serum stability, low off‐target toxicity, and broad applicability,
Tianxing Liu, Lingyu Ke, Ruize Sun, Xiaoling Chen, Mei Zhou, Olaf R. P. Bininda‐Emond, Chengbang Ma, Yangyang Jiang, Tao Wang, Chris Shaw, Lei Wang, Tianbao Chen, Alideertu Dong   +12 more
wiley   +1 more source

Erratum in: MicroRNA-124 Dysregulation Is Associated With Retinal Inflammation and Photoreceptor Death in the Degenerating Retina. [PDF]

Invest Ophthalmol Vis Sci
europepmc   +1 more source

Silent Carriers: The Role of Rodents in the Emergence of Zoonotic Bacterial Threats. [PDF]

Pathogens
Basiouni S, Rodriguez-Morales AJ, Shehata AA, Duarte PM.   +3 more
europepmc   +1 more source

Burrowing pattern and damage caused by the rodent pest, Indian house rat (<i>Rattus rattus</i>) in the Gangetic and Non Gangetic plain of West Bengal, India

, 1970
Debiprasad Chattopadhyay, Nithar Ranjan Madhu, Chanchal Kumar Manna   +2 more
openalex   +2 more sources

In silico prediction of the developmental toxicity of diverse organic chemicals in rodents for regulatory purposes [PDF]

, 2016
Nikita Basant, Shikha Gupta, Kunwar P. Singh   +2 more
openalex   +1 more source

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

Advanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang, Shanfeng Gao, Xiaofan Xiong, Xin Liu, Rufeng Li, Xia Wang, Lin Han, Xuan Xiao, Xiaofei Wang, Wen Li, Yongxia Chang, Yuefeng Du, Juan Yang   +12 more
wiley   +1 more source

Metagenomic insights into host-specific gastroenteritis bacteria in forest rodents of Sarawak, Borneo: implications for one health surveillance of rodent-borne pathogens. [PDF]

BMC Microbiol
Azmi MAI, William-Dee J, Morni MA, Azhar NAA, Sabarudin NA, Jinggong ER, Zolkapley S, Baharom NIM, Haqeem MD, Sien VL, Mohamad Azmi AH, Adrus M, Tan CS, Khan FAA.   +13 more
europepmc   +1 more source