Results 121 to 130 of about 354,195 (312)

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Tracking Spatiotemporal Extracellular Matrix Evolution and Tissue Fusion in 3D Microtissues via Click Chemistry‐Based Metabolic Labelling

Advanced Healthcare Materials, EarlyView.
Metabolic labeling of nascent proteins in 3D microtissue spheroids provides a powerful analytical approach for large‐scale tissue engineering. Incorporation of non‐canonical amino acids with fluorescent tagging enables spatiotemporal investigation of extracellular matrix deposition and its evolution during multicellular tissue development and fusion ...
Theresa Koenig, F. Max Yavitt, Laura Veenendaal, Tim B. F. Woodfield   +3 more
wiley   +1 more source

Digital Twins as a Tool to Improve the Efficiency of Fixed Assets Exploitation in Industry / Цифровые двойники как инструмент повышения эффективности эксплуатации основных средств в промышленности

Beneficium
In the conditions of modern industry, characterized by ever-increasing competition and rapid development of technology, the application of digital twins becomes a key element in the asset management strategy.
Maxim K. Izmaylov / Максим К. Измайлов
doaj   +1 more source

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

Advanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi, Adeline Boyreau, Laura Chaillot, Wilfried Souleyreau, Laetitia Andrique, Pierre‐Olivier Guichet, Thomas Mathivet, Andreas Bikfalvi, Pierre Nassoy   +8 more
wiley   +1 more source

Towards the ROI of Training. A study to get closer to the investment of training interventions in organizations.

reservedQuesta ricerca nasce dall’esigenza di rispondere ad una domanda che non ha trovato risposta nel corso della mia esperienza di lavoro, seppur breve, all’interno i più aziende, fra cui una multinazionale leader di settore a livello globale.
BELTRAMELLO, CESARE
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Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke

Advanced Healthcare Materials, EarlyView.
In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan, Damien Levard, Eloïse Lemarchand, Amal Boublay, Charly Helaine, Jolan Malherbe, Mikaël Naveau, Didier Goux, Igor Khalin, Ankita Talukdar, Cheun Pelleter, Charlène Jacqmarcq, Erwan Baudron, Isabelle Bardou, Sara Martinez de Lizarrondo, Maxime Gauberti, Denis Vivien, Antoine Philippe Fournier   +17 more
wiley   +1 more source

Watermarking medical images by reversible scheme and embedding in region of non-interest

Ho Chi Minh City Open University Journal of Science - Engineering and Technology, 2013
Medical images can be divided into two regions such as region of interest (ROI) and region of non-interest (RONI). We define ROI is the region that contains information of the patient’s state.
Truong Hoang Vinh
doaj  

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Discours du Roi, à l'ouverture du lit de justice, tenu à Versailles le 8 mai 1788 ; Ordonnance du Roi sur l'administration de la justice ; Edit du Roi, portant suppression des tribunaux d'exception ; Déclaration du Roi, relative à l'ordonnance criminelle ([Reprod.])

Collection : Les archives de la Révolution française ; 5.263Collection : Les archives de la Révolution française ; 5.263Comprend : Discours de M. le Garde des Sceaux, pour annoncer l'ordonnance du Roi, sur l'administration de la justice ; Discours de M ...
Louis XVI (1754-1793 ; roi de France). Auteur du texte, Lamoignon, Chrétien-François de (1735-1789). Auteur du texte   +1 more
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An iron triangle ROI model for health care

, 2019
David N van der Goes,1 Nicholas Edwardson,2 Veeshan Rayamajhee,1 Christine Hollis,3 Dawn Hunter4 1Department of Economics, University of New Mexico, Albuquerque, NM, USA; 2School of Public Administration, University of New Mexico, Albuquerque, NM, USA ...
Hunter D, Hollis C, Rayamajhee V, van der Goes DN, Edwardson N   +4 more
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