Results 151 to 160 of about 354,195 (312)

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang   +12 more
wiley   +1 more source

Arrivée du roi à l'Assemblée et son discours, lors de la séance du 19 avril 1791

open access: yes, 1886
Louis XVI, Roi de France . Arrivée du roi à l'Assemblée et son discours, lors de la séance du 19 avril 1791. In: Archives Parlementaires de 1787 à 1860 - Première série (1787-1799) Tome XXV - Du 13 avril 1791 au 11 mai 1791.
Louis XVI, Roi de France
core  

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

open access: yesAdvanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis   +32 more
wiley   +1 more source

Brouillon de pétition du Conseil Législatif au Roi Guillaume IV

open access: yes
22 pages, originalBrouillon de pétition du Conseil Législatif au Roi [Guillaume IV] sur : les efforts de la Chambre d'Assemblée pour augmenter son pouvoir, renverser la constitution du Bas-Canada, prendre le contrôle du revenu provincial et du patronage ...
Ryland, Herman Witsius
core  

Discours du roi, lors de la séance du 5 mai 1789

open access: yes, 1875
Louis XVI, Roi de France . Discours du roi, lors de la séance du 5 mai 1789. In: Archives Parlementaires de 1787 à 1860 - Première série (1787-1799) Tome VIII - Du 5 mai 1789 au 15 septembre 1789. Paris : Librairie Administrative P. Dupont, 1875. pp.
Louis XVI, Roi de France
core  

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

open access: yesAdvanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng   +10 more
wiley   +1 more source

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

open access: yesAdvanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu   +12 more
wiley   +1 more source

Prior Expectations Bias Confidence Judgments Through Parietal Alpha‐Band Modulation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Humans possess the metacognitive ability to estimate the likely accuracy of their own decisions through confidence judgments. Yet, whether prior information shapes confidence and the neural mechanisms mediating such influence, remain to be determined.
Luca Tarasi   +4 more
wiley   +1 more source

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