Results 171 to 180 of about 430,181 (292)

Left Without Being Seen: A Scoping Review of a Silent Crisis in Emergency Departments. [PDF]

open access: yesOpen Access Emerg Med
Ardila Jara AR   +7 more
europepmc   +1 more source

Clinical Course and Predictors of Biologic Therapy, Hospitalisation and Surgery: A Five‐Year Prospective Study in Newly Diagnosed Inflammatory Bowel Disease

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this large multicentre Spanish inception cohort, biologics/JAK inhibitors were frequently used during the first 5 years after inflammatory bowel disease diagnosis and were associated with reduced hospitalisation risk, although not with lower abdominal surgery rates.
Ana Garre   +308 more
wiley   +1 more source

Review of cognitive diagnostic models (CDMs): Recent methodological advancements for addressing practical challenges

open access: yesBritish Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Cognitive diagnostic models (CDMs) have become essential tools for providing fine‐grained information about individuals' mastery of cognitive skills. While prior reviews have emphasized statistical foundations and deep learning‐based developments, this article focuses on recent methodological innovations designed to address persistent ...
Chun Wang, Yale Quan, David Arthur
wiley   +1 more source

Mechanical Small Bowel Obstruction Secondary to Low-Grade Appendiceal Mucinous Neoplasm: A Case Report. [PDF]

open access: yesCureus
Rojas Guanoluisa SA   +4 more
europepmc   +1 more source

Chemoproteomic discovery of a brain‐penetrant, covalent NLRP3 inhibitor that binds a novel allosteric pocket

open access: yesBritish Journal of Pharmacology, EarlyView.
NLRP3 is a promising inflammatory target, but existing inhibitors lack diversity and brain penetrance, and none are approved. Using chemoproteomics, we discovered a novel series that binds to Cys463 in a previously uncharacterized pocket. Compounds showed nanomolar potency, brain exposure, and in vivo suppression of IL‐1β, supporting neuroinflammatory ...
Donald C. Rogness   +21 more
wiley   +1 more source

Mareas rojas

open access: yes, 1989
Las mareas rojas, catástrofes naturales, inevitables y casi siempre impredecibles, se han incrementado notablemente en los últimos años. Con el fin de atenuar sus efectos se implementan hoy diversos sistemas de predicción y control, tarea que aún presenta muchas dificultades.
openaire   +2 more sources

Improving efficiency in conservation planning by modeling species‐specific responses to threat abatement

open access: yesConservation Biology, EarlyView.
Abstract Reversing ongoing biodiversity loss requires effectively managing anthropogenic threats. Although conservation actions can mitigate these threats, prioritizing and targeting such actions remain challenging because species respond differently depending on the nature of the threats and their biological traits.
Camila Guerrero‐Pineda   +3 more
wiley   +1 more source

Publisher Correction: Modeling the Public Health Impact of Introducing 4CMenB Vaccination for Infants in the Brazilian National Immunization Program. [PDF]

open access: yesInfect Dis Ther
Pinto T   +9 more
europepmc   +1 more source

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